Tyrosine Kinase Receptor with Extensive Homology to EGF Receptor Shares Chromosomal Location with <i>neu</i> Oncogene

DOI Web Site 被引用文献52件
  • Lisa Coussens
    Department of Molecular Biology, Genentech, Inc., South San Francisco, CA 94080.
  • Teresa L. Yang-Feng
    Department of Human Genetics at Yale University School of Medicine, New Haven, CT 06510.
  • Yu-Cheng Liao
    Department of Molecular Biology, Genentech, Inc., South San Francisco, CA 94080.
  • Ellson Chen
    Department of Molecular Biology, Genentech, Inc., South San Francisco, CA 94080.
  • Alane Gray
    Department of Molecular Biology, Genentech, Inc., South San Francisco, CA 94080.
  • John McGrath
    Department of Biology, Massachusetts Institute of Technology, Cambridge, MA 02142.
  • Peter H. Seeburg
    Department of Molecular Biology, Genentech, Inc., South San Francisco, CA 94080.
  • Towia A. Libermann
    Department of Chemical Immunology at the Weizmann Institute of Science, Rehovot 76100, Israel.
  • Joseph Schlessinger
    Department of Chemical Immunology at the Weizmann Institute of Science, Rehovot 76100, Israel.
  • Uta Francke
    Department of Human Genetics at Yale University School of Medicine, New Haven, CT 06510.
  • Arthur Levinson
    Department of Molecular Biology, Genentech, Inc., South San Francisco, CA 94080.
  • Axel Ullrich
    Department of Molecular Biology, Genentech, Inc., South San Francisco, CA 94080.

書誌事項

公開日
1985-12-06
DOI
  • 10.1126/science.2999974
公開者
American Association for the Advancement of Science (AAAS)

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説明

<jats:p> A novel potential cell surface receptor of the tyrosine kinase gene family has been identified and characterized by molecular cloning. Its primary sequence is very similar to that of the human epidermal growth factor receptor and the v-erbB oncogene product; the chromosomal location of the gene for this protein is coincident with the <jats:italic>neu</jats:italic> oncogene, which suggests that the two genes may be identical. </jats:p>

収録刊行物

  • Science

    Science 230 (4730), 1132-1139, 1985-12-06

    American Association for the Advancement of Science (AAAS)

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