C. Diff Quik Chek Complete Enzyme Immunoassay Provides a Reliable First-Line Method for Detection of <i>Clostridium difficile</i> in Stool Specimens

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<jats:title>ABSTRACT</jats:title> <jats:p> We evaluated a single membrane device assay for simultaneously detecting both <jats:italic>Clostridium difficile</jats:italic> glutamate dehydrogenase (GDH) and toxin A/B antigens against a standard that combines two PCR assays and cytotoxigenic culture. Results showing dual GDH and toxin A/B antigen positives and negatives can be reported immediately as true positives and negatives, respectively. Specimens with discrepant results for GDH and toxins A/B, which comprised 13.2% of the specimens, need to be retested. </jats:p>

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