Combined Effects of Child and Adult Elevated Blood Pressure on Subclinical Atherosclerosis

DOI Web Site 被引用文献1件
  • Jonna Juhola
    From the Research Centre of Applied and Preventive Cardiovascular Medicine and the Departments of Clinical Physiology and Nuclear Medicine and Medicine, University of Turku and Turku University Hospital, Turku, Finland (J.J., C.G.M., J.S.A.V., O.T.R., M.J.); Menzies Research Institute Tasmania, University of Tasmania, Hobart, Australia (C.G.M., A.V.); Tulane Center for Cardiovascular Health, Tulane University, New Orleans, LA (G.S.B., S.R.S., W.C.); Department of Epidemiology, College of Public...
  • Costan G. Magnussen
    From the Research Centre of Applied and Preventive Cardiovascular Medicine and the Departments of Clinical Physiology and Nuclear Medicine and Medicine, University of Turku and Turku University Hospital, Turku, Finland (J.J., C.G.M., J.S.A.V., O.T.R., M.J.); Menzies Research Institute Tasmania, University of Tasmania, Hobart, Australia (C.G.M., A.V.); Tulane Center for Cardiovascular Health, Tulane University, New Orleans, LA (G.S.B., S.R.S., W.C.); Department of Epidemiology, College of Public...
  • Gerald S. Berenson
    From the Research Centre of Applied and Preventive Cardiovascular Medicine and the Departments of Clinical Physiology and Nuclear Medicine and Medicine, University of Turku and Turku University Hospital, Turku, Finland (J.J., C.G.M., J.S.A.V., O.T.R., M.J.); Menzies Research Institute Tasmania, University of Tasmania, Hobart, Australia (C.G.M., A.V.); Tulane Center for Cardiovascular Health, Tulane University, New Orleans, LA (G.S.B., S.R.S., W.C.); Department of Epidemiology, College of Public...
  • Alison Venn
    From the Research Centre of Applied and Preventive Cardiovascular Medicine and the Departments of Clinical Physiology and Nuclear Medicine and Medicine, University of Turku and Turku University Hospital, Turku, Finland (J.J., C.G.M., J.S.A.V., O.T.R., M.J.); Menzies Research Institute Tasmania, University of Tasmania, Hobart, Australia (C.G.M., A.V.); Tulane Center for Cardiovascular Health, Tulane University, New Orleans, LA (G.S.B., S.R.S., W.C.); Department of Epidemiology, College of Public...
  • Trudy L. Burns
    From the Research Centre of Applied and Preventive Cardiovascular Medicine and the Departments of Clinical Physiology and Nuclear Medicine and Medicine, University of Turku and Turku University Hospital, Turku, Finland (J.J., C.G.M., J.S.A.V., O.T.R., M.J.); Menzies Research Institute Tasmania, University of Tasmania, Hobart, Australia (C.G.M., A.V.); Tulane Center for Cardiovascular Health, Tulane University, New Orleans, LA (G.S.B., S.R.S., W.C.); Department of Epidemiology, College of Public...
  • Matthew A. Sabin
    From the Research Centre of Applied and Preventive Cardiovascular Medicine and the Departments of Clinical Physiology and Nuclear Medicine and Medicine, University of Turku and Turku University Hospital, Turku, Finland (J.J., C.G.M., J.S.A.V., O.T.R., M.J.); Menzies Research Institute Tasmania, University of Tasmania, Hobart, Australia (C.G.M., A.V.); Tulane Center for Cardiovascular Health, Tulane University, New Orleans, LA (G.S.B., S.R.S., W.C.); Department of Epidemiology, College of Public...
  • Sathanur R. Srinivasan
    From the Research Centre of Applied and Preventive Cardiovascular Medicine and the Departments of Clinical Physiology and Nuclear Medicine and Medicine, University of Turku and Turku University Hospital, Turku, Finland (J.J., C.G.M., J.S.A.V., O.T.R., M.J.); Menzies Research Institute Tasmania, University of Tasmania, Hobart, Australia (C.G.M., A.V.); Tulane Center for Cardiovascular Health, Tulane University, New Orleans, LA (G.S.B., S.R.S., W.C.); Department of Epidemiology, College of Public...
  • Stephen R. Daniels
    From the Research Centre of Applied and Preventive Cardiovascular Medicine and the Departments of Clinical Physiology and Nuclear Medicine and Medicine, University of Turku and Turku University Hospital, Turku, Finland (J.J., C.G.M., J.S.A.V., O.T.R., M.J.); Menzies Research Institute Tasmania, University of Tasmania, Hobart, Australia (C.G.M., A.V.); Tulane Center for Cardiovascular Health, Tulane University, New Orleans, LA (G.S.B., S.R.S., W.C.); Department of Epidemiology, College of Public...
  • Patricia H. Davis
    From the Research Centre of Applied and Preventive Cardiovascular Medicine and the Departments of Clinical Physiology and Nuclear Medicine and Medicine, University of Turku and Turku University Hospital, Turku, Finland (J.J., C.G.M., J.S.A.V., O.T.R., M.J.); Menzies Research Institute Tasmania, University of Tasmania, Hobart, Australia (C.G.M., A.V.); Tulane Center for Cardiovascular Health, Tulane University, New Orleans, LA (G.S.B., S.R.S., W.C.); Department of Epidemiology, College of Public...
  • Wei Chen
    From the Research Centre of Applied and Preventive Cardiovascular Medicine and the Departments of Clinical Physiology and Nuclear Medicine and Medicine, University of Turku and Turku University Hospital, Turku, Finland (J.J., C.G.M., J.S.A.V., O.T.R., M.J.); Menzies Research Institute Tasmania, University of Tasmania, Hobart, Australia (C.G.M., A.V.); Tulane Center for Cardiovascular Health, Tulane University, New Orleans, LA (G.S.B., S.R.S., W.C.); Department of Epidemiology, College of Public...
  • Mika Kähönen
    From the Research Centre of Applied and Preventive Cardiovascular Medicine and the Departments of Clinical Physiology and Nuclear Medicine and Medicine, University of Turku and Turku University Hospital, Turku, Finland (J.J., C.G.M., J.S.A.V., O.T.R., M.J.); Menzies Research Institute Tasmania, University of Tasmania, Hobart, Australia (C.G.M., A.V.); Tulane Center for Cardiovascular Health, Tulane University, New Orleans, LA (G.S.B., S.R.S., W.C.); Department of Epidemiology, College of Public...
  • Leena Taittonen
    From the Research Centre of Applied and Preventive Cardiovascular Medicine and the Departments of Clinical Physiology and Nuclear Medicine and Medicine, University of Turku and Turku University Hospital, Turku, Finland (J.J., C.G.M., J.S.A.V., O.T.R., M.J.); Menzies Research Institute Tasmania, University of Tasmania, Hobart, Australia (C.G.M., A.V.); Tulane Center for Cardiovascular Health, Tulane University, New Orleans, LA (G.S.B., S.R.S., W.C.); Department of Epidemiology, College of Public...
  • Elaine Urbina
    From the Research Centre of Applied and Preventive Cardiovascular Medicine and the Departments of Clinical Physiology and Nuclear Medicine and Medicine, University of Turku and Turku University Hospital, Turku, Finland (J.J., C.G.M., J.S.A.V., O.T.R., M.J.); Menzies Research Institute Tasmania, University of Tasmania, Hobart, Australia (C.G.M., A.V.); Tulane Center for Cardiovascular Health, Tulane University, New Orleans, LA (G.S.B., S.R.S., W.C.); Department of Epidemiology, College of Public...
  • Jorma S.A. Viikari
    From the Research Centre of Applied and Preventive Cardiovascular Medicine and the Departments of Clinical Physiology and Nuclear Medicine and Medicine, University of Turku and Turku University Hospital, Turku, Finland (J.J., C.G.M., J.S.A.V., O.T.R., M.J.); Menzies Research Institute Tasmania, University of Tasmania, Hobart, Australia (C.G.M., A.V.); Tulane Center for Cardiovascular Health, Tulane University, New Orleans, LA (G.S.B., S.R.S., W.C.); Department of Epidemiology, College of Public...
  • Terence Dwyer
    From the Research Centre of Applied and Preventive Cardiovascular Medicine and the Departments of Clinical Physiology and Nuclear Medicine and Medicine, University of Turku and Turku University Hospital, Turku, Finland (J.J., C.G.M., J.S.A.V., O.T.R., M.J.); Menzies Research Institute Tasmania, University of Tasmania, Hobart, Australia (C.G.M., A.V.); Tulane Center for Cardiovascular Health, Tulane University, New Orleans, LA (G.S.B., S.R.S., W.C.); Department of Epidemiology, College of Public...
  • Olli T. Raitakari
    From the Research Centre of Applied and Preventive Cardiovascular Medicine and the Departments of Clinical Physiology and Nuclear Medicine and Medicine, University of Turku and Turku University Hospital, Turku, Finland (J.J., C.G.M., J.S.A.V., O.T.R., M.J.); Menzies Research Institute Tasmania, University of Tasmania, Hobart, Australia (C.G.M., A.V.); Tulane Center for Cardiovascular Health, Tulane University, New Orleans, LA (G.S.B., S.R.S., W.C.); Department of Epidemiology, College of Public...
  • Markus Juonala
    From the Research Centre of Applied and Preventive Cardiovascular Medicine and the Departments of Clinical Physiology and Nuclear Medicine and Medicine, University of Turku and Turku University Hospital, Turku, Finland (J.J., C.G.M., J.S.A.V., O.T.R., M.J.); Menzies Research Institute Tasmania, University of Tasmania, Hobart, Australia (C.G.M., A.V.); Tulane Center for Cardiovascular Health, Tulane University, New Orleans, LA (G.S.B., S.R.S., W.C.); Department of Epidemiology, College of Public...

書誌事項

タイトル別名
  • The International Childhood Cardiovascular Cohort Consortium

抄録

<jats:sec> <jats:title>Background—</jats:title> <jats:p>Elevated blood pressure (BP) levels in childhood have been associated with subsequent atherosclerosis. However, it is uncertain whether this risk is attenuated in individuals who acquire normal BP by adulthood. The present study examined the effect of child and adult BP levels on carotid artery intima-media thickness (IMT) in adulthood.</jats:p> </jats:sec> <jats:sec> <jats:title>Methods and Results—</jats:title> <jats:p>The cohort consisted of 4210 participants from 4 prospective studies (mean follow-up, 23 years). Childhood elevated BP was defined according to the tables from the National High Blood Pressure Education Program. In adulthood, BP was classified as elevated for individuals with systolic BP ≥120 mm Hg, diastolic BP ≥80 mm Hg or with self-reported use of antihypertensive medications. Carotid artery IMT was measured in the left common carotid artery. High IMT was defined as an IMT ≥90th percentile according to age-, sex-, race-, and cohort-specific levels. Individuals with persistently elevated BP and individuals with normal childhood BP, but elevated adult BP had increased risk of high carotid artery IMT (relative risk [95% confidence interval]) 1.82[1.47–2.38] and 1.57[1.22–2.02], respectively) in comparison with individuals with normal child and adult BP. In contrast, individuals with elevated BP as children but not as adults did not have significantly increased risk (1.24[0.92–1.67]). In addition, these individuals had a lower risk of increased carotid artery IMT (0.66[0.50–0.88]) in compared with those with persistently elevated BP. The results were consistent when controlling for age, sex, and adiposity and when different BP definitions were applied.</jats:p> </jats:sec> <jats:sec> <jats:title>Conclusions—</jats:title> <jats:p>Individuals with persistently elevated BP from childhood to adulthood had increased risk of carotid atherosclerosis. This risk was reduced if elevated BP during childhood resolved by adulthood.</jats:p> </jats:sec>

収録刊行物

  • Circulation

    Circulation 128 (3), 217-224, 2013-07-16

    Ovid Technologies (Wolters Kluwer Health)

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