Hyperosmolar and Other Types of Nonketoacidotic Coma in Diabetes

  • T S Danowski
    Section of Endocrinology and Metabolism of the Department of Medicine of the University of Pittsburgh, the Medical Center and Shadyside Hospitals Pittsburgh Pennsylvania and the Institute of Clinical Research of the Middlesex Hospital Medical School London, England
  • J D N Nabarro
    Section of Endocrinology and Metabolism of the Department of Medicine of the University of Pittsburgh, the Medical Center and Shadyside Hospitals Pittsburgh Pennsylvania and the Institute of Clinical Research of the Middlesex Hospital Medical School London, England

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<jats:p>In patients with hyperosmolality as the sole cause or as an important factor in the production of the coma, therapy with hypotonic or isotonic fluids and with insulin, often in amounts less than those generally used in diabetic ketoacidosis, has proved effective in restoring consciousness in many, but not all, instances of hyperosmolar coma. The mortality, however, has been high, usually because of uremia, stroke, massive infection, pancreatitis, etc.</jats:p>

収録刊行物

  • Diabetes

    Diabetes 14 (3), 162-165, 1965-03-01

    American Diabetes Association

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