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- Baltazar Zavala
- Experimental Neurology Group Nuffield Department of Clinical Neurology University of Oxford John Radcliffe Hospital Oxford UK
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- Kareem Zaghloul
- Surgical Neurology Branch National Institutes of Health Bethesda MD USA
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- Peter Brown
- Experimental Neurology Group Nuffield Department of Clinical Neurology University of Oxford John Radcliffe Hospital Oxford UK
説明
<jats:title>Abstract</jats:title><jats:p>The subthalamic nucleus (STN), which is currently the most common target for deep brain stimulation (DBS) for Parkinson's disease (PD), has received increased attention over the past few years for the roles it may play in functions beyond simple motor control. In this article, we highlight several of the theoretical, interventional, and electrophysiological studies that have implicated the STN in response inhibition. Most influential among this evidence has been the reported effect of STN DBS in increasing impulsive responses in the laboratory setting. Yet, how this relates to pathological impulsivity in patients' everyday lives remains uncertain. © 2015 International Parkinson and Movement Disorder Society</jats:p>
収録刊行物
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- Movement Disorders
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Movement Disorders 30 (3), 328-338, 2015-02-17
Wiley