Physiologic Events of Embryo Implantation and Decidualization in Human and Non-Human Primates

  • Maria Ariadna Ochoa-Bernal
    Department of Obstetrics, Gynecology & Reproductive Biology, Michigan State University, Grand Rapids, MI 49503, USA
  • Asgerally T. Fazleabas
    Department of Obstetrics, Gynecology & Reproductive Biology, Michigan State University, Grand Rapids, MI 49503, USA

書誌事項

公開日
2020-03-13
権利情報
  • https://creativecommons.org/licenses/by/4.0/
DOI
  • 10.3390/ijms21061973
公開者
MDPI AG

説明

<jats:p>Reproduction is a fundamental process for the preservation of the human species. This process requires a sequence of orchestrated events that are necessary for a successful pregnancy. Two of the most critical steps in the establishment of human pregnancy are implantation and decidualization, which are required for maternal interactions with the developing embryo. This review primarily highlights the physiological aspects of these two events and the adverse pregnancy outcomes from defective implantation and decidualization. The focus of this review is to provide a general concept of the mechanisms involved during the window of implantation, description of components involved in the process and possible pathologies that could disrupt the embryo implantation and decidualization and specifically as it applies to women and non-human primates.</jats:p>

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