Effective Inhibition of SARS-CoV-2 Entry by Heparin and Enoxaparin Derivatives

DOI Web Site 3 Citations
  • Ritesh Tandon
    Department of Microbiology and Immunology, University of Mississippi Medical Center, Jackson, Mississippi, USA
  • Joshua S. Sharp
    Department of BioMolecular Sciences, University of Mississippi, Oxford, Mississippi, USA
  • Fuming Zhang
    Center for Biotechnology and Interdisciplinary Studies, Rensselaer Polytechnic Institute, Troy, New York, USA
  • Vitor H. Pomin
    Department of BioMolecular Sciences, University of Mississippi, Oxford, Mississippi, USA
  • Nicole M. Ashpole
    Department of BioMolecular Sciences, University of Mississippi, Oxford, Mississippi, USA
  • Dipanwita Mitra
    Department of Microbiology and Immunology, University of Mississippi Medical Center, Jackson, Mississippi, USA
  • Martin G. McCandless
    Department of Microbiology and Immunology, University of Mississippi Medical Center, Jackson, Mississippi, USA
  • Weihua Jin
    Center for Biotechnology and Interdisciplinary Studies, Rensselaer Polytechnic Institute, Troy, New York, USA
  • Hao Liu
    Department of BioMolecular Sciences, University of Mississippi, Oxford, Mississippi, USA
  • Poonam Sharma
    Department of Microbiology and Immunology, University of Mississippi Medical Center, Jackson, Mississippi, USA
  • Robert J. Linhardt
    Center for Biotechnology and Interdisciplinary Studies, Rensselaer Polytechnic Institute, Troy, New York, USA
  • Tom Gallagher
    editor

Description

<jats:p>The emergence of severe acute respiratory syndrome coronavirus (SARS-CoV-2) in Wuhan, China, in late 2019 and its subsequent spread to the rest of the world has created a pandemic situation unprecedented in modern history. While ACE2 has been identified as the viral receptor, cellular polysaccharides have also been implicated in virus entry.</jats:p>

Journal

  • Journal of Virology

    Journal of Virology 95 (3), e01987-, 2021-01-13

    American Society for Microbiology

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