Aligning Coronary Anatomy and Myocardial Perfusion Territories

DOI Web Site 被引用文献2件
  • Rodrigo J. Cerci
    From the Division of Cardiology (R.J.C., A.A-Z., R.T.G., J.M.M., V.M., K.Y., A.L.V., J.T., W.G., J.B., J.A.C.L.,) and the Bloomberg School of Public Health (C.C.), Johns Hopkins University, Baltimore, MD; and Brigham and Women’s Hospital, Harvard University, Boston, MA (C.F., M.D.C.).
  • Armin Arbab-Zadeh
    From the Division of Cardiology (R.J.C., A.A-Z., R.T.G., J.M.M., V.M., K.Y., A.L.V., J.T., W.G., J.B., J.A.C.L.,) and the Bloomberg School of Public Health (C.C.), Johns Hopkins University, Baltimore, MD; and Brigham and Women’s Hospital, Harvard University, Boston, MA (C.F., M.D.C.).
  • Richard T. George
    From the Division of Cardiology (R.J.C., A.A-Z., R.T.G., J.M.M., V.M., K.Y., A.L.V., J.T., W.G., J.B., J.A.C.L.,) and the Bloomberg School of Public Health (C.C.), Johns Hopkins University, Baltimore, MD; and Brigham and Women’s Hospital, Harvard University, Boston, MA (C.F., M.D.C.).
  • Julie M. Miller
    From the Division of Cardiology (R.J.C., A.A-Z., R.T.G., J.M.M., V.M., K.Y., A.L.V., J.T., W.G., J.B., J.A.C.L.,) and the Bloomberg School of Public Health (C.C.), Johns Hopkins University, Baltimore, MD; and Brigham and Women’s Hospital, Harvard University, Boston, MA (C.F., M.D.C.).
  • Andrea L. Vavere
    From the Division of Cardiology (R.J.C., A.A-Z., R.T.G., J.M.M., V.M., K.Y., A.L.V., J.T., W.G., J.B., J.A.C.L.,) and the Bloomberg School of Public Health (C.C.), Johns Hopkins University, Baltimore, MD; and Brigham and Women’s Hospital, Harvard University, Boston, MA (C.F., M.D.C.).
  • Vishal Mehra
    From the Division of Cardiology (R.J.C., A.A-Z., R.T.G., J.M.M., V.M., K.Y., A.L.V., J.T., W.G., J.B., J.A.C.L.,) and the Bloomberg School of Public Health (C.C.), Johns Hopkins University, Baltimore, MD; and Brigham and Women’s Hospital, Harvard University, Boston, MA (C.F., M.D.C.).
  • Kihei Yoneyama
    From the Division of Cardiology (R.J.C., A.A-Z., R.T.G., J.M.M., V.M., K.Y., A.L.V., J.T., W.G., J.B., J.A.C.L.,) and the Bloomberg School of Public Health (C.C.), Johns Hopkins University, Baltimore, MD; and Brigham and Women’s Hospital, Harvard University, Boston, MA (C.F., M.D.C.).
  • John Texter
    From the Division of Cardiology (R.J.C., A.A-Z., R.T.G., J.M.M., V.M., K.Y., A.L.V., J.T., W.G., J.B., J.A.C.L.,) and the Bloomberg School of Public Health (C.C.), Johns Hopkins University, Baltimore, MD; and Brigham and Women’s Hospital, Harvard University, Boston, MA (C.F., M.D.C.).
  • Courtney Foster
    From the Division of Cardiology (R.J.C., A.A-Z., R.T.G., J.M.M., V.M., K.Y., A.L.V., J.T., W.G., J.B., J.A.C.L.,) and the Bloomberg School of Public Health (C.C.), Johns Hopkins University, Baltimore, MD; and Brigham and Women’s Hospital, Harvard University, Boston, MA (C.F., M.D.C.).
  • Wei Guo
    From the Division of Cardiology (R.J.C., A.A-Z., R.T.G., J.M.M., V.M., K.Y., A.L.V., J.T., W.G., J.B., J.A.C.L.,) and the Bloomberg School of Public Health (C.C.), Johns Hopkins University, Baltimore, MD; and Brigham and Women’s Hospital, Harvard University, Boston, MA (C.F., M.D.C.).
  • Christopher Cox
    From the Division of Cardiology (R.J.C., A.A-Z., R.T.G., J.M.M., V.M., K.Y., A.L.V., J.T., W.G., J.B., J.A.C.L.,) and the Bloomberg School of Public Health (C.C.), Johns Hopkins University, Baltimore, MD; and Brigham and Women’s Hospital, Harvard University, Boston, MA (C.F., M.D.C.).
  • Jeffrey Brinker
    From the Division of Cardiology (R.J.C., A.A-Z., R.T.G., J.M.M., V.M., K.Y., A.L.V., J.T., W.G., J.B., J.A.C.L.,) and the Bloomberg School of Public Health (C.C.), Johns Hopkins University, Baltimore, MD; and Brigham and Women’s Hospital, Harvard University, Boston, MA (C.F., M.D.C.).
  • Marcelo Di Carli
    From the Division of Cardiology (R.J.C., A.A-Z., R.T.G., J.M.M., V.M., K.Y., A.L.V., J.T., W.G., J.B., J.A.C.L.,) and the Bloomberg School of Public Health (C.C.), Johns Hopkins University, Baltimore, MD; and Brigham and Women’s Hospital, Harvard University, Boston, MA (C.F., M.D.C.).
  • Joao A.C. Lima
    From the Division of Cardiology (R.J.C., A.A-Z., R.T.G., J.M.M., V.M., K.Y., A.L.V., J.T., W.G., J.B., J.A.C.L.,) and the Bloomberg School of Public Health (C.C.), Johns Hopkins University, Baltimore, MD; and Brigham and Women’s Hospital, Harvard University, Boston, MA (C.F., M.D.C.).

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タイトル別名
  • An Algorithm for the CORE320 Multicenter Study

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<jats:sec> <jats:title>Background—</jats:title> <jats:p>Appropriate clinical decisions concerning diagnosis and treatment of coronary artery disease rely on correct integration of data on coronary anatomy and myocardial perfusion. The purpose of this article is to introduce a new left ventricular segmentation model for improved alignment of coronary arterial segments and myocardial perfusion territories, designed for the CORE320 study.</jats:p> </jats:sec> <jats:sec> <jats:title>Methods and Results—</jats:title> <jats:p>CORE320 is a prospective, multicenter study with a primary objective to evaluate the diagnostic accuracy of 320-row detector computed tomography (CT) to detect coronary artery luminal stenosis and corresponding myocardial perfusion deficits in patients with suspected coronary artery disease compared with the gold standard of conventional coronary angiography and single-photon emission CT myocardial perfusion imaging. We describe a 19-coronary segment and 13-myocardial territory alignment model, its application in both standard and CT image data sets, and the adjudication process of the initial cohort of patients recruited for the CORE320 study. Adjudication committees reviewed the images of the first 101 gold standard and 107 CT data sets. On the basis of the presented model and rules, all cases for adjudication were correctly identified. During image review, 6 (5.9%) gold standard and 9 (8.4%) CT data sets needed further realignment not triggered by the algorithm.</jats:p> </jats:sec> <jats:sec> <jats:title>Conclusions—</jats:title> <jats:p>We present a vascular territory distribution model developed for the CORE320 multicenter study, which accounts for variability in coronary anatomy and potential myocardial perfusion territory overlap.</jats:p> </jats:sec> <jats:sec> <jats:title>Clinical Trial Registration—</jats:title> <jats:p> URL: <jats:ext-link xmlns:xlink="http://www.w3.org/1999/xlink" ext-link-type="uri" xlink:href="http://www.clinicaltrials.gov">http://www.clinicaltrials.gov</jats:ext-link> . Unique identifier: NCT00934037. </jats:p> </jats:sec>

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