hBD‐1: a novel β‐defensin from human plasma

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書誌事項

公開日
1995-07-17
権利情報
  • http://onlinelibrary.wiley.com/termsAndConditions#vor
DOI
  • 10.1016/0014-5793(95)00687-5
公開者
Wiley

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説明

<jats:p>We report the isolation and characterization of a novel peptide with significant sequence homology to β‐defensins from human blood filtrate. The human β‐defensin‐1 (hBD‐1) is a short basic peptide of 36 amino acid residues. It contains six cysteines forming three intramolecular disulfide bonds. The molecular mass of hBD‐1 is 3928.6 Da. Cloning of the specific cDNA confirmed the amino acid sequence of the native peptide. hBD‐1 shares the nine conserved amino acids characteristic for β‐defensins from respiratory epithelial cells and neutrophils of cattle and chicken leukocytes. hBD‐1 is present in nanomolar concentration in human plasma.</jats:p>

収録刊行物

  • FEBS Letters

    FEBS Letters 368 (2), 331-335, 1995-07-17

    Wiley

被引用文献 (21)*注記

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