Diagnosis and Classification of 17 Diseases from 1404 Subjects <i>via</i> Pattern Analysis of Exhaled Molecules

Morad K. Nakhleh, Haitham Amal, Raneen Jeries, Yoav Y. Broza, Manal Aboud, Alaa Gharra, Hodaya Ivgi, Salam Khatib, Shifaa Badarneh, Lior Har-Shai, Lea Glass-Marmor, Izabella Lejbkowicz, Ariel Miller, Samih Badarny, Raz Winer, John Finberg, Sylvia Cohen-Kaminsky, Frédéric Perros, David Montani, Barbara Girerd, Gilles Garcia, Gérald Simonneau, Farid Nakhoul, Shira Baram, Raed Salim, Marwan Hakim, Maayan Gruber, Ohad Ronen, Tal Marshak, Ilana Doweck, Ofer Nativ, Zaher Bahouth, Da-you Shi, Wei Zhang, Qing-ling Hua, Yue-yin Pan, Li Tao, Hu Liu, Amir Karban, Eduard Koifman, Tova Rainis, Roberts Skapars, Armands Sivins, Guntis Ancans, Inta Liepniece-Karele, Ilze Kikuste, Ieva Lasina, Ivars Tolmanis, Douglas Johnson, Stuart Z. Millstone, Jennifer Fulton, John W. Wells, Larry H. Wilf, Marc Humbert, Marcis Leja, Nir Peled, Hossam Haick

doi:10.1021/acsnano.6b04930

Diagnosis and Classification of 17 Diseases from 1404 Subjects <i>via</i> Pattern Analysis of Exhaled Molecules

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Morad K. Nakhleh

Department of Chemical Engineering and Russell Berrie Nanotechnology Institute, Technion−Israel Institute of Technology, Haifa 3200003, Israel
Haitham Amal

Department of Chemical Engineering and Russell Berrie Nanotechnology Institute, Technion−Israel Institute of Technology, Haifa 3200003, Israel
Raneen Jeries

Department of Chemical Engineering and Russell Berrie Nanotechnology Institute, Technion−Israel Institute of Technology, Haifa 3200003, Israel
Yoav Y. Broza

Department of Chemical Engineering and Russell Berrie Nanotechnology Institute, Technion−Israel Institute of Technology, Haifa 3200003, Israel
Manal Aboud

Department of Chemical Engineering and Russell Berrie Nanotechnology Institute, Technion−Israel Institute of Technology, Haifa 3200003, Israel
Alaa Gharra

Department of Chemical Engineering and Russell Berrie Nanotechnology Institute, Technion−Israel Institute of Technology, Haifa 3200003, Israel
Hodaya Ivgi

Department of Chemical Engineering and Russell Berrie Nanotechnology Institute, Technion−Israel Institute of Technology, Haifa 3200003, Israel
Salam Khatib

Department of Chemical Engineering and Russell Berrie Nanotechnology Institute, Technion−Israel Institute of Technology, Haifa 3200003, Israel
Shifaa Badarneh

Department of Chemical Engineering and Russell Berrie Nanotechnology Institute, Technion−Israel Institute of Technology, Haifa 3200003, Israel
Lior Har-Shai

Division of Neuroimmunology and Multiple Sclerosis Center, Carmel Medical Center and Rappaport Family Faculty of Medicine, Technion−Israel Institute of Technology, Haifa 31096, Israel
Lea Glass-Marmor

Division of Neuroimmunology and Multiple Sclerosis Center, Carmel Medical Center and Rappaport Family Faculty of Medicine, Technion−Israel Institute of Technology, Haifa 31096, Israel
Izabella Lejbkowicz

Division of Neuroimmunology and Multiple Sclerosis Center, Carmel Medical Center and Rappaport Family Faculty of Medicine, Technion−Israel Institute of Technology, Haifa 31096, Israel
Ariel Miller

Division of Neuroimmunology and Multiple Sclerosis Center, Carmel Medical Center and Rappaport Family Faculty of Medicine, Technion−Israel Institute of Technology, Haifa 31096, Israel
Samih Badarny

Movement Disorders Clinic, Department of Neurology, Carmel Medical Center, and Rappaport Family Faculty of Medicine, Technion−Israel Institute of Technology, Haifa 31096, Israel
Raz Winer

Movement Disorders Clinic, Department of Neurology, Carmel Medical Center, and Rappaport Family Faculty of Medicine, Technion−Israel Institute of Technology, Haifa 31096, Israel
John Finberg

Department of Molecular Pharmacology, Rappaport Family Faculty of Medicine, Technion−Israel Institute of Technology, Haifa 31096, Israel
Sylvia Cohen-Kaminsky

Univ. Paris-Sud, Faculté de Médecine, Université Paris-Saclay, AP-HP, Centre National de Référence de l′Hypertension Pulmonaire Sévère, Département Hospitalo-Universitaire (DHU) Thorax Innovation, Service de Pneumologie, Hôpital de Bicêtre, UMRS _999, INSERM and Univ. Paris−Sud, Laboratoire d’Excellence (LabEx) en Recherche sur le Médicament et l′Innovation Thérapeutique (LERMIT), Centre Chirurgical Marie Lannelongue, Le Plessis Robinson 92350, France
Frédéric Perros

Univ. Paris-Sud, Faculté de Médecine, Université Paris-Saclay, AP-HP, Centre National de Référence de l′Hypertension Pulmonaire Sévère, Département Hospitalo-Universitaire (DHU) Thorax Innovation, Service de Pneumologie, Hôpital de Bicêtre, UMRS _999, INSERM and Univ. Paris−Sud, Laboratoire d’Excellence (LabEx) en Recherche sur le Médicament et l′Innovation Thérapeutique (LERMIT), Centre Chirurgical Marie Lannelongue, Le Plessis Robinson 92350, France
David Montani

Univ. Paris-Sud, Faculté de Médecine, Université Paris-Saclay, AP-HP, Centre National de Référence de l′Hypertension Pulmonaire Sévère, Département Hospitalo-Universitaire (DHU) Thorax Innovation, Service de Pneumologie, Hôpital de Bicêtre, UMRS _999, INSERM and Univ. Paris−Sud, Laboratoire d’Excellence (LabEx) en Recherche sur le Médicament et l′Innovation Thérapeutique (LERMIT), Centre Chirurgical Marie Lannelongue, Le Plessis Robinson 92350, France
Barbara Girerd

Univ. Paris-Sud, Faculté de Médecine, Université Paris-Saclay, AP-HP, Centre National de Référence de l′Hypertension Pulmonaire Sévère, Département Hospitalo-Universitaire (DHU) Thorax Innovation, Service de Pneumologie, Hôpital de Bicêtre, UMRS _999, INSERM and Univ. Paris−Sud, Laboratoire d’Excellence (LabEx) en Recherche sur le Médicament et l′Innovation Thérapeutique (LERMIT), Centre Chirurgical Marie Lannelongue, Le Plessis Robinson 92350, France
Gilles Garcia

Univ. Paris-Sud, Faculté de Médecine, Université Paris-Saclay, AP-HP, Centre National de Référence de l′Hypertension Pulmonaire Sévère, Département Hospitalo-Universitaire (DHU) Thorax Innovation, Service de Pneumologie, Hôpital de Bicêtre, UMRS _999, INSERM and Univ. Paris−Sud, Laboratoire d’Excellence (LabEx) en Recherche sur le Médicament et l′Innovation Thérapeutique (LERMIT), Centre Chirurgical Marie Lannelongue, Le Plessis Robinson 92350, France
Gérald Simonneau

Univ. Paris-Sud, Faculté de Médecine, Université Paris-Saclay, AP-HP, Centre National de Référence de l′Hypertension Pulmonaire Sévère, Département Hospitalo-Universitaire (DHU) Thorax Innovation, Service de Pneumologie, Hôpital de Bicêtre, UMRS _999, INSERM and Univ. Paris−Sud, Laboratoire d’Excellence (LabEx) en Recherche sur le Médicament et l′Innovation Thérapeutique (LERMIT), Centre Chirurgical Marie Lannelongue, Le Plessis Robinson 92350, France
Farid Nakhoul

Department of Nephrology and Hypertension Baruch Padeh Medical Center, Poriya 15208, Israel
Shira Baram

Department of Obstetrics and Gynecology, Emek Medical Center, Afula 18101, and Rappaport Family Faculty of Medicine, Technion−Israel Institute of Technology, Haifa 31096, Israel
Raed Salim

Department of Obstetrics and Gynecology, Emek Medical Center, Afula 18101, and Rappaport Family Faculty of Medicine, Technion−Israel Institute of Technology, Haifa 31096, Israel
Marwan Hakim

Department of Obstetrics and Gynecology, Nazareth Hospital EMMS, Nazareth, and Faculty of Medicine in the Galilee, Bar Ilan University, Ramat Gan, Israel
Maayan Gruber

The Department of Otolaryngology Head and Neck Surgery, Carmel Medical Center, Haifa 3436212, Israel
Ohad Ronen

The Department of Otolaryngology Head and Neck Surgery, Carmel Medical Center, Haifa 3436212, Israel
Tal Marshak

The Department of Otolaryngology Head and Neck Surgery, Carmel Medical Center, Haifa 3436212, Israel
Ilana Doweck

The Department of Otolaryngology Head and Neck Surgery, Carmel Medical Center, Haifa 3436212, Israel
Ofer Nativ

Department of Urology, Bnai Zion Medical Center, Haifa 31048, Israel
Zaher Bahouth

Department of Urology, Bnai Zion Medical Center, Haifa 31048, Israel
Da-you Shi

Department of Oncology, The First Affiliated Hospital of Anhui Medical University, Hefei 230032, China
Wei Zhang

Department of Oncology, The First Affiliated Hospital of Anhui Medical University, Hefei 230032, China
Qing-ling Hua

Department of Oncology, The First Affiliated Hospital of Anhui Medical University, Hefei 230032, China
Yue-yin Pan

Department of Oncology, The First Affiliated Hospital of Anhui Medical University, Hefei 230032, China
Li Tao

Department of Oncology, The First Affiliated Hospital of Anhui Medical University, Hefei 230032, China
Hu Liu

Department of Oncology, The First Affiliated Hospital of Anhui Medical University, Hefei 230032, China
Amir Karban

Internal Medicine C and Gastroenterology Departments, Rambam Medical Center, Rappaport Family Faculty of Medicine, Technion−Israel Institute of Technology, Haifa 3525408, Israel
Eduard Koifman

Internal Medicine C and Gastroenterology Departments, Rambam Medical Center, Rappaport Family Faculty of Medicine, Technion−Israel Institute of Technology, Haifa 3525408, Israel
Tova Rainis

Department of Gastroenterology, Bnai Zion Hospital and Rappaport Family Faculty of Medicine, Technion−Israel Institute of Technology, Haifa 31096, Israel
Roberts Skapars

Faculty of Medicine, University of Latvia, Digestive Diseases, Riga East University Hospital, 19 Rainisboulv, LV1586 Riga, Latvia
Armands Sivins

Faculty of Medicine, University of Latvia, Digestive Diseases, Riga East University Hospital, 19 Rainisboulv, LV1586 Riga, Latvia
Guntis Ancans

Faculty of Medicine, University of Latvia, Digestive Diseases, Riga East University Hospital, 19 Rainisboulv, LV1586 Riga, Latvia
Inta Liepniece-Karele

Faculty of Medicine, University of Latvia, Digestive Diseases, Riga East University Hospital, 19 Rainisboulv, LV1586 Riga, Latvia
Ilze Kikuste

Faculty of Medicine, University of Latvia, Digestive Diseases, Riga East University Hospital, 19 Rainisboulv, LV1586 Riga, Latvia
Ieva Lasina

Faculty of Medicine, University of Latvia, Digestive Diseases, Riga East University Hospital, 19 Rainisboulv, LV1586 Riga, Latvia
Ivars Tolmanis

Digestive Diseases Centre, GASTRO, 6 Linezeraiela, LV1006 Riga, Latvia
Douglas Johnson

Department of Radiation Oncology, Baptist Cancer Institute (BCI), 1235 San Marco Boulevard, Suite100, Jacksonville, Florida 32207, United States
Stuart Z. Millstone

Pulmonary and Critical Care Associates, Orange Park, Florida 32073, United States
Jennifer Fulton

Pulmonary Diseases, Baptist Medical Center, Jacksonville, Florida 32217, United States
John W. Wells

Pulmonary and Critical Care Associates, Orange Park, Florida 32073, United States
Larry H. Wilf

Oncologic Imaging Division, Florida Radiation Oncology Group, Jacksonville, Florida 32217, United States
Marc Humbert

Univ. Paris-Sud, Faculté de Médecine, Université Paris-Saclay, AP-HP, Centre National de Référence de l′Hypertension Pulmonaire Sévère, Département Hospitalo-Universitaire (DHU) Thorax Innovation, Service de Pneumologie, Hôpital de Bicêtre, UMRS _999, INSERM and Univ. Paris−Sud, Laboratoire d’Excellence (LabEx) en Recherche sur le Médicament et l′Innovation Thérapeutique (LERMIT), Centre Chirurgical Marie Lannelongue, Le Plessis Robinson 92350, France
Marcis Leja

Faculty of Medicine, University of Latvia, Digestive Diseases, Riga East University Hospital, 19 Rainisboulv, LV1586 Riga, Latvia
Nir Peled

Thoracic Cancer Unit, Davidoff Cancer Center, RMC, Kaplan Street, Petach Tiqwa 49100, Israel
Hossam Haick

Department of Chemical Engineering and Russell Berrie Nanotechnology Institute, Technion−Israel Institute of Technology, Haifa 3200003, Israel