A novel approach to the solubility measurement of protein crystals by two-beam interferometry

Gen Sazaki, Kazuo Kurihara, Toshitaka Nakada, Satoru Miyashita, Hiroshi Komatsu

doi:10.1016/s0022-0248(96)00442-3

A novel approach to the solubility measurement of protein crystals by two-beam interferometry

DOI Web Site Web Site 被引用文献9件

この論文をさがす

CiNii Books

説明

Abstract A novel technique was developed for the rapid solubility measurement of protein crystals (lysozyme) by two-beam interferometry. The merits of this technique are: (1) time saving (less than 2 h to obtain one experimental point), (2) the small amount of the sample (∼66 μl), (3) high accuracy, (4) applicable to the solubility measurement of a metastable phase and (5) insensitive to impurities. The limitations of the present technique are also discussed.