Acylation of indoles via photoredox catalysis: a route to 3-acylindoles

  • Lijun Gu
    Key Laboratory of Chemistry in Ethnic Medicinal Resources
  • Cheng Jin
    New United Group Company Limited
  • Jiyan Liu
    Key Laboratory of Chemistry in Ethnic Medicinal Resources
  • Hongtao Zhang
    Key Laboratory of Chemistry in Ethnic Medicinal Resources
  • Minglong Yuan
    Engineering Research Center of Biopolymer Functional Materials of Yunnan
  • Ganpeng Li
    Key Laboratory of Chemistry in Ethnic Medicinal Resources

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Description

<p>A visible-light-catalyzed synthesis of 3-acylindoles from simple indoles and α-oxo acids at room temperature has been discovered. This method offers rapid access to 3-acylindoles through C–C and C–H bond activation.</p>

Journal

  • Green Chemistry

    Green Chemistry 18 (5), 1201-1205, 2016

    Royal Society of Chemistry (RSC)

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