Action of Light on Frog Pigment Cells in Culture

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書誌事項

公開日
1990-01
権利情報
  • http://onlinelibrary.wiley.com/termsAndConditions#vor
DOI
  • 10.1111/j.1600-0749.1990.tb00260.x
公開者
Wiley

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説明

<jats:p>Solar radiation induces numerous biologic effects in skin but the mechanism underlying these responses is poorly understood. To study the etiology of these phenomena, we investigated the effect of light on cultured <jats:italic>Xenopus laevis</jats:italic> melanophores. Visible light stimulated a marked increase in intracellular cAMP levels within the first minute of irradiation. This light‐induced elevation in cAMP was blocked by melatonin and was not seen in fibroblasts irradiated in a similar manner. These data show that the photoresponse of pigment cells from amphibian skin can be mediated by a cAMP‐dependent mechanism and suggest that a unique member of the rhodopsin family is involved in this process.</jats:p>

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