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- David A. Gold
- Department of Earth, Atmospheric and Planetary Science, Massachusetts Institute of Technology, Cambridge, MA 02139;
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- Jonathan Grabenstatter
- Department of Earth, Atmospheric and Planetary Science, Massachusetts Institute of Technology, Cambridge, MA 02139;
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- Alex de Mendoza
- Institut de Biologia Evolutiva (Consejo Superior de Investigaciones CientÍficas-Universitat Pompeu Fabra), 08003 Barcelona, Spain;
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- Ana Riesgo
- Department of Life Sciences, Natural History Museum of London, London SW7 5BD, United Kingdom;
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- Iñaki Ruiz-Trillo
- Institut de Biologia Evolutiva (Consejo Superior de Investigaciones CientÍficas-Universitat Pompeu Fabra), 08003 Barcelona, Spain;
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- Roger E. Summons
- Department of Earth, Atmospheric and Planetary Science, Massachusetts Institute of Technology, Cambridge, MA 02139;
書誌事項
- 公開日
- 2016-02-22
- 権利情報
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- http://www.pnas.org/preview_site/misc/userlicense.xhtml
- DOI
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- 10.1073/pnas.1512614113
- 公開者
- Proceedings of the National Academy of Sciences
この論文をさがす
説明
<jats:title>Significance</jats:title><jats:p>An unusual molecule is found in rocks ∼650–540 million y old, and its likely precursor, 24-isopropylcholesterol (24-ipc), is produced by some modern sea sponges. The sterane hydrocarbon analog of 24-ipc offers a potential “molecular fossil” for early animals, but certain algae also produce traces of this molecule, so it is unclear when and how frequently the ability to synthesize 24-ipc evolved. In this study, we connect 24-ipc production to a gene and conclude that algae and sponges independently evolved 24-ipc synthesis through unique gene duplication events. Although the timing of the sponge gene duplication overlaps with the geological record of the molecular fossil, the algal gene duplication occurs significantly later, supporting the connection of 24-ipc to sponges and providing the oldest evidence for animal life.</jats:p>
収録刊行物
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- Proceedings of the National Academy of Sciences
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Proceedings of the National Academy of Sciences 113 (10), 2684-2689, 2016-02-22
Proceedings of the National Academy of Sciences
