<i>Salacia</i>Extract Improves Postprandial Glucose and Insulin Response: A Randomized Double-Blind, Placebo Controlled, Crossover Study in Healthy Volunteers

  • Shankaranarayanan Jeykodi
    Research and Development, OmniActive Health Technologies Ltd., Mumbai, India
  • Jayant Deshpande
    Research and Development, OmniActive Health Technologies Inc., Prince Edward Island, Canada
  • Vijaya Juturu
    Scientific and Clinical Affairs, OmniActive Health Technologies Inc., Morristown, NJ, USA

説明

<jats:p>Thirty-five healthy subjects were randomly assigned to different doses of<jats:italic>Salacia chinensis</jats:italic>extract (200 mg, 300 mg, and 500 mg SCE) capsules and compared with placebo. It is a placebo controlled randomized crossover design study. Subjects were given oral sucrose solution along with capsules and plasma glucose and insulin responses were analyzed. Blood samples were collected at 0, 30, 60, 90, 120, and 180 minutes after administration. AUC insulin significantly lowered after ingestion of SCE. No significant adverse events were observed. Reducing glucose and insulin is very important in reducing postprandial hyperglycemia.</jats:p>

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