<scp>EAACI</scp> guidelines on allergen immunotherapy: Hymenoptera venom allergy
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- G. J. Sturm
- Department of Dermatology and Venerology Medical University of Graz Graz Austria
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- E.‐M. Varga
- Department of Paediatric and Adolescent Medicine Respiratory and Allergic Disease Division Medical University of Graz Graz Austria
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- G. Roberts
- The David Hide Asthma and Allergy Research Centre St Mary's Hospital, Newport, Isle of Wight NIHR Biomedical Research Centre University Hospital Southampton NHS Foundation Trust Southampton UK
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- H. Mosbech
- Allergy Clinic Copenhagen University Hospital Gentofte Gentofte Denmark
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- M. B. Bilò
- Allergy Unit Department of Internal Medicine University Hospital of Ancona Ancona Italy
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- C. A. Akdis
- Swiss Institute of Allergy and Asthma Research (SIAF) University of Zurich Zurich Switzerland
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- D. Antolín‐Amérigo
- Servicio de Enfermedades del Sistema Inmune‐Alergia Departamento de Medicina y Especialidades Médicas Hospital Universitario Príncipe de Asturias Universidad de Alcalá Madrid Spain
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- E. Cichocka‐Jarosz
- Department of Pediatrics Jagiellonian University Medical College Krakow Poland
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- R. Gawlik
- Department of Internal Medicine, Allergy and Clinical Immunology Medical University of Silesia Katowice Poland
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- T. Jakob
- Department of Dermatology and Allergology University Medical Center Gießen and Marburg (UKGM) Justus Liebig University Gießen Gießen Germany
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- M. Kosnik
- Medical Faculty Ljubljana University Clinic of Respiratory and Allergic Diseases Golnik Ljubljana Slovenia
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- J. Lange
- Department of Pediatric Pneumonology and Allergy Medical University of Warsaw Warsaw Poland
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- E. Mingomataj
- Department of Allergology & Clinical Immunology Mother Theresa School of Medicine Tirana Albania
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- D. I. Mitsias
- Department of Allergy and Clinical Immunology 2nd Paediatric Clinic University of Athens Athens Greece
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- M. Ollert
- Department of Infection and Immunity Luxembourg Institute of Health (LIH) Strassen Luxembourg
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- J. N. G. Oude Elberink
- Department of Allergology and Internal Medicine University of Groningen University Medical Hospital Groningen & Groningen Research Center for Asthma and COPD (GRIAC) Groningen The Netherlands
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- O. Pfaar
- Department of Otorhinolaryngology, Head and Neck Surgery Medical Faculty Mannheim Universitätsmedizin Mannheim Heidelberg University Heidelberg Germany
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- C. Pitsios
- Medical School University of Cyprus Nicosia Cyprus
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- V. Pravettoni
- UOC Clinical Allergy and Immunology ‐ IRCCS Foundation Ca’ Granda Ospedale Maggiore Policlinico Milan Italy
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- F. Ruëff
- Klinik und Poliklinik für Dermatologie und Allergologie Klinikum der Universität München Munich Germany
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- B. A. Sin
- Department of Pulmonary Diseases Division of Immunology and Allergy Faculty of Medicine Ankara University Ankara Turkey
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- I. Agache
- Faculty of Medicine Department of Allergy and Clinical Immunology Transylvania University Brasov Brasov Romania
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- E. Angier
- Department of Immunology and Allergy Northern General Hospital Sheffield UK
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- S. Arasi
- Department of Pediatrics Allergy Unit University of Messina Messina Italy
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- M. A. Calderón
- Section of Allergy and Clinical Immunology Imperial College London National Heart and Lung Institute Royal Brompton Hospital London UK
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- M. Fernandez‐Rivas
- Allergy Department Hospital Clínico San Carlos IdISSC Madrid Spain
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- S. Halken
- Hans Christian Andersen Children's Hospital Odense University Hospital Odense Denmark
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- M. Jutel
- Wroclaw Medical University Wroclaw Poland
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- S. Lau
- Department of Pediatric Pneumology and Immunology Charité Universitätsmedizin Berlin Germany
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- G. B. Pajno
- Department of Pediatrics Allergy Unit University of Messina Messina Italy
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- R. van Ree
- Departments of Experimental Immunology and of Otorhinolaryngology Academic Medical Center University of Amsterdam Amsterdam The Netherlands
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- D. Ryan
- Usher Institute of Population Health Sciences and Informatics University of Edinburgh Edinburgh UK
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- O. Spranger
- Austrian Lung Union Vienna Austria
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- R. G. van Wijk
- Section of Allergology Department of Internal Medicine Erasmus MC Rotterdam Rotterdam The Netherlands
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- S. Dhami
- Evidence‐Based Health Care Ltd Edinburgh UK
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- H. Zaman
- School of Pharmacy University of Bradford Bradford UK
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- A. Sheikh
- Asthma UK Centre for Applied Research Usher Institute of Population Health Sciences and Informatics University of Edinburgh Edinburgh UK
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- A. Muraro
- Food Allergy Referral Centre Veneto Region Department of Women and Child Health Padua General University Hospital Padua Italy
説明
<jats:title>Abstract</jats:title><jats:p>Hymenoptera venom allergy is a potentially life‐threatening allergic reaction following a honeybee, vespid, or ant sting. Systemic‐allergic sting reactions have been reported in up to 7.5% of adults and up to 3.4% of children. They can be mild and restricted to the skin or moderate to severe with a risk of life‐threatening anaphylaxis. Patients should carry an emergency kit containing an adrenaline autoinjector, H<jats:sub>1</jats:sub>‐antihistamines, and corticosteroids depending on the severity of their previous sting reaction(s). The only treatment to prevent further systemic sting reactions is venom immunotherapy. This guideline has been prepared by the European Academy of Allergy and Clinical Immunology's (<jats:styled-content style="fixed-case">EAACI</jats:styled-content>) Taskforce on Venom Immunotherapy as part of the <jats:styled-content style="fixed-case">EAACI</jats:styled-content> Guidelines on Allergen Immunotherapy initiative. The guideline aims to provide evidence‐based recommendations for the use of venom immunotherapy, has been informed by a formal systematic review and meta‐analysis and produced using the Appraisal of Guidelines for Research and Evaluation (<jats:styled-content style="fixed-case">AGREE II</jats:styled-content>) approach. The process included representation from a range of stakeholders. Venom immunotherapy is indicated in venom‐allergic children and adults to prevent further moderate‐to‐severe systemic sting reactions. Venom immunotherapy is also recommended in adults with only generalized skin reactions as it results in significant improvements in quality of life compared to carrying an adrenaline autoinjector. This guideline aims to give practical advice on performing venom immunotherapy. Key sections cover general considerations before initiating venom immunotherapy, evidence‐based clinical recommendations, risk factors for adverse events and for relapse of systemic sting reaction, and a summary of gaps in the evidence.</jats:p>
収録刊行物
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- Allergy
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Allergy 73 (4), 744-764, 2017-12-05
Wiley