Expanding the Scope of the Organocatalytic Addition of Fluorobis(phenylsulfonyl)methane to Enals: Enantioselective Cascade Synthesis of Fluoroindane and Fluorochromanol Derivatives
抄録
<jats:title>Abstract</jats:title><jats:p>Highly enantioselective cascade reactions for the synthesis of fluoroindanes and chromanols derivatives are described. The cascade reactions consisted of either a double Michael reaction or Michael–hemiacetal formation <jats:italic>via</jats:italic> the addition of fluorobis(phenylsulfonyl)methane (FBSM) to enals. The final products were obtained in good yields with excellent stereoselectivities.</jats:p><jats:p><jats:boxed-text content-type="graphic" position="anchor"><jats:graphic xmlns:xlink="http://www.w3.org/1999/xlink" mimetype="image/gif" position="anchor" specific-use="enlarged-web-image" xlink:href="graphic/mcontent.gif"><jats:alt-text>magnified image</jats:alt-text></jats:graphic></jats:boxed-text></jats:p>
収録刊行物
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- Advanced Synthesis & Catalysis
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Advanced Synthesis & Catalysis 356 (2-3), 437-446, 2014-01-20
Wiley