書誌事項
- 公開日
- 1991-06
- 権利情報
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- http://onlinelibrary.wiley.com/termsAndConditions#vor
- DOI
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- 10.1111/j.1365-2958.1991.tb00779.x
- 公開者
- Wiley
この論文をさがす
説明
<jats:title>Summary</jats:title><jats:p>The <jats:italic>arsR</jats:italic> gene encodes the regulatory protein of the plasmid‐encoded arsenical resistance operon. A series of in‐frame fusions was constructed between the <jats:italic>C</jats:italic>‐terminally truncated <jats:italic>arsR</jats:italic> gene and the coding region for the mature form of β‐lactamase <jats:italic>(blaM).</jats:italic> Fusions containing most of the <jats:italic>arsR</jats:italic> gene were still inducible by arsenicals. Fusions containing less than 102 residues of the 117‐residue ArsR protein were constitutive. When a wild‐type <jats:italic>arsR</jats:italic> gene was placed <jats:italic>in trans</jats:italic>, the constitutive constructs were again inducible. The results demonstrate that the ArsR protein is a trans‐acting regulatory protein which controls its own expression.</jats:p>
収録刊行物
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- Molecular Microbiology
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Molecular Microbiology 5 (6), 1331-1336, 1991-06
Wiley