Effects of Sairei-To on the Relapse of Steroid-Dependent Nephrotic Syndrome

Kenijiro Kimura, Shinichiro Nanba, Akihiro Tojo, Hiroaki Matsuoka, Tsuneaki Sugimoto

doi:10.1142/s0192415x90000071

Effects of Sairei-To on the Relapse of Steroid-Dependent Nephrotic Syndrome

DOI Web Site PubMed 被引用文献3件

Kenijiro Kimura

The Second Department of Internal Medicine, Faculty of Medicine, the University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, Japan
Shinichiro Nanba

The Second Department of Internal Medicine, Faculty of Medicine, the University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, Japan
Akihiro Tojo

The Second Department of Internal Medicine, Faculty of Medicine, the University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, Japan
Hiroaki Matsuoka

The Second Department of Internal Medicine, Faculty of Medicine, the University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, Japan
Tsuneaki Sugimoto

The Second Department of Internal Medicine, Faculty of Medicine, the University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, Japan

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<jats:p> Sairei-To (Chai-Ling-Tang) was administered to four patients with steroid-dependent relapsing nephrotic syndrome. It was associated with prednisolone and immunosuppressive agents. Histological diagnosis was minimal change in three patients and mild focal glomerulonephritis in one patient. After the start of Sairei-To administration the relapse was markedly suppressed in three patients but not at all in the other. Although we could consider Sairei-To effective for steroid-dependent nephrotic syndrome in the present study, a larger study is necessary to confirm its efficacy. </jats:p>