Dual Photoredox/Nickel‐Catalyzed Three‐Component Carbofunctionalization of Alkenes

  • Andrés García‐Domínguez
    Department of Chemistry University of Zurich Winterthurerstrasse 190 8057 Zurich Switzerland
  • Rahul Mondal
    Department of Chemistry University of Zurich Winterthurerstrasse 190 8057 Zurich Switzerland
  • Cristina Nevado
    Department of Chemistry University of Zurich Winterthurerstrasse 190 8057 Zurich Switzerland

書誌事項

公開日
2019-07-25
権利情報
  • http://onlinelibrary.wiley.com/termsAndConditions#vor
DOI
  • 10.1002/ange.201906692
公開者
Wiley

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説明

<jats:title>Abstract</jats:title><jats:p>The potential of merging photoredox and nickel catalysis to perform multicomponent alkene difunctionalizations under visible‐light irradiation is demonstrated here. Secondary and tertiary alkyl groups, as well as sulfonyl moieties can be added to the terminal position of the double bond with simultaneous arylation of the internal carbon atom in a single step under mild reaction conditions. The process, devoid of stoichiometric additives, benefits from the use of bench‐stable and easy‐to‐handle reagents, is operationally simple, and tolerates a wide variety of functional groups.</jats:p>

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