Stereoselective Synthesis of α‐Trifluoromethyl Enones by Au<sup>I</sup>/Cu<sup>I</sup>‐Co‐Catalyzed Tandem 1,3‐Acyloxy Migration/Trifluoromethylation Reaction of Propargyl Acetates
書誌事項
- 公開日
- 2014-10-29
- 権利情報
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- http://onlinelibrary.wiley.com/termsAndConditions#vor
- DOI
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- 10.1002/ejoc.201403115
- 公開者
- Wiley
この論文をさがす
説明
<jats:title>Abstract</jats:title><jats:p>Au<jats:sup>I</jats:sup>/Cu<jats:sup>I</jats:sup>‐co‐catalyzed tandem 1,3‐acyloxy migration/trifluoromethylation reaction of propargyl esters to give α‐trifluoromethyl enones in moderate yields and with excellent stereoselectivity is described. It is proposed that the reaction proceeds through the 1,3‐acyloxy migration of the propargyl esters catalyzed by Au<jats:sup>I</jats:sup> to produce an allenic intermediate, followed by its trifluoromethylation to give the final product.</jats:p>
収録刊行物
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- European Journal of Organic Chemistry
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European Journal of Organic Chemistry 2014 (35), 7948-7954, 2014-10-29
Wiley