Chemical and physical basics of routine formaldehyde fixation

  • Rooban Thavarajah
    Department of OralandMaxillofacial Pathology, Ragas Dental College and Hospital, Uthandi, Chennai, India
  • Vidya Kazhiyur Mudimbaimannar
    Department of OralandMaxillofacial Pathology, Ragas Dental College and Hospital, Uthandi, Chennai, India
  • Joshua Elizabeth
    Department of OralandMaxillofacial Pathology, Ragas Dental College and Hospital, Uthandi, Chennai, India
  • Umadevi Krishnamohan Rao
    Department of OralandMaxillofacial Pathology, Ragas Dental College and Hospital, Uthandi, Chennai, India
  • Kannan Ranganathan
    Department of OralandMaxillofacial Pathology, Ragas Dental College and Hospital, Uthandi, Chennai, India

書誌事項

公開日
2012-09
DOI
  • 10.4103/0973-029x.102496
公開者
Ovid Technologies (Wolters Kluwer Health)

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説明

<jats:p>Formaldehyde is the widely employed fixative that has been studied for decades. The chemistry of fixation has been studied widely since the early 20<jats:sup>th</jats:sup> century. However, very few studies have been focused on the actual physics/chemistry aspect of process of this fixation. This article attempts to explain the chemistry of formaldehyde fixation and also to study the physical aspects involved in the fixation. The factors involved in the fixation process are discussed using well documented mathematical and physical formulae. The deeper understanding of these factors will enable pathologist to optimize the factors and use them in their favor.</jats:p>

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