Synthesis of 3-trifluoromethylpyrazoles via trifluoromethylation/cyclization of α,β-alkynic hydrazones using a hypervalent iodine reagent

  • Guojing Ji
    Beijing National Laboratory of Molecular Sciences (BNLMS) and Key Laboratory of Bioorganic Chemistry and Molecular Engineering of Ministry of Education
  • Xi Wang
    Beijing National Laboratory of Molecular Sciences (BNLMS) and Key Laboratory of Bioorganic Chemistry and Molecular Engineering of Ministry of Education
  • Songnan Zhang
    Beijing National Laboratory of Molecular Sciences (BNLMS) and Key Laboratory of Bioorganic Chemistry and Molecular Engineering of Ministry of Education
  • Yan Xu
    Beijing National Laboratory of Molecular Sciences (BNLMS) and Key Laboratory of Bioorganic Chemistry and Molecular Engineering of Ministry of Education
  • Yuxuan Ye
    Beijing National Laboratory of Molecular Sciences (BNLMS) and Key Laboratory of Bioorganic Chemistry and Molecular Engineering of Ministry of Education
  • Ming Li
    College of Chemistry and Molecular Engineering
  • Yan Zhang
    Beijing National Laboratory of Molecular Sciences (BNLMS) and Key Laboratory of Bioorganic Chemistry and Molecular Engineering of Ministry of Education
  • Jianbo Wang
    Beijing National Laboratory of Molecular Sciences (BNLMS) and Key Laboratory of Bioorganic Chemistry and Molecular Engineering of Ministry of Education

書誌事項

公開日
2014
DOI
  • 10.1039/c4cc01280a
公開者
Royal Society of Chemistry (RSC)

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説明

<p>A mild and efficient method for the synthesis of 3-trifluoromethylpyrazoles has been established <italic>via</italic> trifluoromethylation/cyclization of α,β-alkynic hydrazones using a hypervalent iodine reagent.</p>

収録刊行物

  • Chem. Commun.

    Chem. Commun. 50 (33), 4361-4363, 2014

    Royal Society of Chemistry (RSC)

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