Jammed Microgel Inks for 3D Printing Applications
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- Christopher B. Highley
- Department of Bioengineering University of Pennsylvania 210 South 33rd Street Philadelphia PA 19104 USA
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- Kwang Hoon Song
- Department of Bioengineering University of Pennsylvania 210 South 33rd Street Philadelphia PA 19104 USA
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- Andrew C. Daly
- Department of Bioengineering University of Pennsylvania 210 South 33rd Street Philadelphia PA 19104 USA
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- Jason A. Burdick
- Department of Bioengineering University of Pennsylvania 210 South 33rd Street Philadelphia PA 19104 USA
書誌事項
- 公開日
- 2018-10-24
- 権利情報
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- http://creativecommons.org/licenses/by/4.0/
- http://creativecommons.org/licenses/by/4.0/
- DOI
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- 10.1002/advs.201801076
- 公開者
- Wiley
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説明
<jats:title>Abstract</jats:title><jats:p>3D printing involves the development of inks that exhibit the requisite properties for both printing and the intended application. In bioprinting, these inks are often hydrogels with controlled rheological properties that can be stabilized after deposition. Here, an alternate approach is developed where the ink is composed exclusively of jammed microgels, which are designed to incorporate a range of properties through microgel design (e.g., composition, size) and through the mixing of microgels. The jammed microgel inks are shear‐thinning to permit flow and rapidly recover upon deposition, including on surfaces or when deposited in 3D within hydrogel supports, and can be further stabilized with secondary cross‐linking. This platform allows the use of microgels engineered from various materials (e.g., thiol‐ene cross‐linked hyaluronic acid (HA), photo‐cross‐linked poly(ethylene glycol), thermo‐sensitive agarose) and that incorporate cells, where the jamming process and printing do not decrease cell viability. The versatility of this particle‐based approach opens up numerous potential biomedical applications through the printing of a more diverse set of inks.</jats:p>
収録刊行物
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- Advanced Science
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Advanced Science 6 (1), 1801076-, 2018-10-24
Wiley
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詳細情報 詳細情報について
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- CRID
- 1363670320089483776
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- ISSN
- 21983844
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- Web Site
- https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1002%2Fadvs.201801076
- https://onlinelibrary.wiley.com/doi/pdf/10.1002/advs.201801076
- https://onlinelibrary.wiley.com/doi/full-xml/10.1002/advs.201801076
- https://onlinelibrary.wiley.com/doi/am-pdf/10.1002%2Fadvs.201801076
- https://advanced.onlinelibrary.wiley.com/doi/pdf/10.1002/advs.201801076
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