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- Tiffany J. Morris
- 1 Medical Genomics, and 2Statistical Genomics, UCL Cancer Institute, University College London, London WC1E 6BT, UK, 3CAS-MPG Partner Institute for Computational Biology, Shanghai Institute for Biological Sciences, Shanghai 200031, China and 4Institute of Environmental Medicine, Karolinska Instytutet, 17177 Stockholm, Sweden
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- Lee M. Butcher
- 1 Medical Genomics, and 2Statistical Genomics, UCL Cancer Institute, University College London, London WC1E 6BT, UK, 3CAS-MPG Partner Institute for Computational Biology, Shanghai Institute for Biological Sciences, Shanghai 200031, China and 4Institute of Environmental Medicine, Karolinska Instytutet, 17177 Stockholm, Sweden
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- Andrew Feber
- 1 Medical Genomics, and 2Statistical Genomics, UCL Cancer Institute, University College London, London WC1E 6BT, UK, 3CAS-MPG Partner Institute for Computational Biology, Shanghai Institute for Biological Sciences, Shanghai 200031, China and 4Institute of Environmental Medicine, Karolinska Instytutet, 17177 Stockholm, Sweden
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- Andrew E. Teschendorff
- 1 Medical Genomics, and 2Statistical Genomics, UCL Cancer Institute, University College London, London WC1E 6BT, UK, 3CAS-MPG Partner Institute for Computational Biology, Shanghai Institute for Biological Sciences, Shanghai 200031, China and 4Institute of Environmental Medicine, Karolinska Instytutet, 17177 Stockholm, Sweden
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- Ankur R. Chakravarthy
- 1 Medical Genomics, and 2Statistical Genomics, UCL Cancer Institute, University College London, London WC1E 6BT, UK, 3CAS-MPG Partner Institute for Computational Biology, Shanghai Institute for Biological Sciences, Shanghai 200031, China and 4Institute of Environmental Medicine, Karolinska Instytutet, 17177 Stockholm, Sweden
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- Tomasz K. Wojdacz
- 1 Medical Genomics, and 2Statistical Genomics, UCL Cancer Institute, University College London, London WC1E 6BT, UK, 3CAS-MPG Partner Institute for Computational Biology, Shanghai Institute for Biological Sciences, Shanghai 200031, China and 4Institute of Environmental Medicine, Karolinska Instytutet, 17177 Stockholm, Sweden
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- Stephan Beck
- 1 Medical Genomics, and 2Statistical Genomics, UCL Cancer Institute, University College London, London WC1E 6BT, UK, 3CAS-MPG Partner Institute for Computational Biology, Shanghai Institute for Biological Sciences, Shanghai 200031, China and 4Institute of Environmental Medicine, Karolinska Instytutet, 17177 Stockholm, Sweden
書誌事項
- 公開日
- 2013-12-12
- DOI
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- 10.1093/bioinformatics/btt684
- 公開者
- Oxford University Press (OUP)
この論文をさがす
説明
<jats:title>Abstract</jats:title> <jats:p>The Illumina Infinium HumanMethylation450 BeadChip is a new platform for high-throughput DNA methylation analysis. Several methods for normalization and processing of these data have been published recently. Here we present an integrated analysis pipeline offering a choice of the most popular normalization methods while also introducing new methods for calling differentially methylated regions and detecting copy number aberrations.</jats:p> <jats:p>Availability and implementation: ChAMP is implemented as a Bioconductor package in R. The package and the vignette can be downloaded at bioconductor.org</jats:p> <jats:p>Contact: tiffany.morris@ucl.ac.uk</jats:p>
収録刊行物
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- Bioinformatics
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Bioinformatics 30 (3), 428-430, 2013-12-12
Oxford University Press (OUP)
