Babesiosis and blood transfusion: flying under the radar

書誌事項

公開日
2006-02-28
権利情報
  • http://onlinelibrary.wiley.com/termsAndConditions#vor
DOI
  • 10.1111/j.1423-0410.2006.00740.x
公開者
Wiley

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説明

<jats:p>Infectious agents of disease continue to plague transfusion medicine as an increasing number of pathogens are described that pose a potential blood safety risk. While the recent focus has been on newly emerged agents, several well‐established pathogens provide timely reminders that other agents continue to pose threats, but invariably ‘fly under the radar’, thereby failing to elicit adequate measures to prevent their transmission by blood transfusion. Perhaps foremost among this group of agents are the <jats:italic>Babesia</jats:italic> spp., which have been known to cause human disease, in the USA, for close to 40 years. <jats:italic>B. microti</jats:italic>, <jats:italic>B. divergens</jats:italic> and several <jats:italic>Babesia</jats:italic>‐like agents are responsible for a growing number of human babesiosis infections. Concomitantly, in the USA, there has been a sharp rise in the number of transfusion‐transmitted infections of <jats:italic>Babesia</jats:italic> spp., attributable almost exclusively to <jats:italic>B. microti</jats:italic>. Despite the obvious public health issues posed by <jats:italic>Babesia</jats:italic> spp., options for preventing their transmission by blood transfusion remain limited. However, recognition that the <jats:italic>Babesia</jats:italic> spp. are indeed an ongoing and expanding blood safety threat will probably prove instrumental in the development of viable interventions to limit transmission of these agents.</jats:p>

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