An Exocyclic Methylene Group Acts As a Bioisostere of the 2′-Oxygen Atom in LNA

DOI Web Site 被引用文献14件
  • Punit P. Seth
    Departments of Medicinal Chemistry, Structural Biology, and Antisense Drug Discovery, Isis Pharmaceuticals, Inc., 1891 Rutherford Road, Carlsbad, California 92008, and Department of Biochemistry, Vanderbilt University, School of Medicine, Nashville, Tennessee 37232
  • Charles R. Allerson
    Departments of Medicinal Chemistry, Structural Biology, and Antisense Drug Discovery, Isis Pharmaceuticals, Inc., 1891 Rutherford Road, Carlsbad, California 92008, and Department of Biochemistry, Vanderbilt University, School of Medicine, Nashville, Tennessee 37232
  • Andres Berdeja
    Departments of Medicinal Chemistry, Structural Biology, and Antisense Drug Discovery, Isis Pharmaceuticals, Inc., 1891 Rutherford Road, Carlsbad, California 92008, and Department of Biochemistry, Vanderbilt University, School of Medicine, Nashville, Tennessee 37232
  • Andrew Siwkowski
    Departments of Medicinal Chemistry, Structural Biology, and Antisense Drug Discovery, Isis Pharmaceuticals, Inc., 1891 Rutherford Road, Carlsbad, California 92008, and Department of Biochemistry, Vanderbilt University, School of Medicine, Nashville, Tennessee 37232
  • Pradeep S. Pallan
    Departments of Medicinal Chemistry, Structural Biology, and Antisense Drug Discovery, Isis Pharmaceuticals, Inc., 1891 Rutherford Road, Carlsbad, California 92008, and Department of Biochemistry, Vanderbilt University, School of Medicine, Nashville, Tennessee 37232
  • Hans Gaus
    Departments of Medicinal Chemistry, Structural Biology, and Antisense Drug Discovery, Isis Pharmaceuticals, Inc., 1891 Rutherford Road, Carlsbad, California 92008, and Department of Biochemistry, Vanderbilt University, School of Medicine, Nashville, Tennessee 37232
  • Thazha P. Prakash
    Departments of Medicinal Chemistry, Structural Biology, and Antisense Drug Discovery, Isis Pharmaceuticals, Inc., 1891 Rutherford Road, Carlsbad, California 92008, and Department of Biochemistry, Vanderbilt University, School of Medicine, Nashville, Tennessee 37232
  • Andrew T. Watt
    Departments of Medicinal Chemistry, Structural Biology, and Antisense Drug Discovery, Isis Pharmaceuticals, Inc., 1891 Rutherford Road, Carlsbad, California 92008, and Department of Biochemistry, Vanderbilt University, School of Medicine, Nashville, Tennessee 37232
  • Martin Egli
    Departments of Medicinal Chemistry, Structural Biology, and Antisense Drug Discovery, Isis Pharmaceuticals, Inc., 1891 Rutherford Road, Carlsbad, California 92008, and Department of Biochemistry, Vanderbilt University, School of Medicine, Nashville, Tennessee 37232
  • Eric E. Swayze
    Departments of Medicinal Chemistry, Structural Biology, and Antisense Drug Discovery, Isis Pharmaceuticals, Inc., 1891 Rutherford Road, Carlsbad, California 92008, and Department of Biochemistry, Vanderbilt University, School of Medicine, Nashville, Tennessee 37232

書誌事項

公開日
2010-10-01
DOI
  • 10.1021/ja105875e
公開者
American Chemical Society (ACS)

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