Polylactic Acid Based Nanocomposites: Promising Safe and Biodegradable Materials in Biomedical Field

  • Lili Sha
    College of Material Science and Technology, Nanjing University of Aeronautics and Astronautics, Nanjing 210016, China
  • Zhaofeng Chen
    College of Material Science and Technology, Nanjing University of Aeronautics and Astronautics, Nanjing 210016, China
  • Zhou Chen
    College of Material Science and Technology, Nanjing University of Aeronautics and Astronautics, Nanjing 210016, China
  • Aili Zhang
    Nanoscale Science and Engineering Center, The Ohio State University, Columbus, OH 43210, USA
  • Zhaogang Yang
    Nanoscale Science and Engineering Center, The Ohio State University, Columbus, OH 43210, USA

書誌事項

公開日
2016
権利情報
  • http://creativecommons.org/licenses/by/4.0/
DOI
  • 10.1155/2016/6869154
公開者
Wiley

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説明

<jats:p>Polylactic acid (PLA) is widely used in biological areas due to its excellent compatibility, bioabsorbability, and degradation behavior in human bodies. Pure polylactic acid has difficulty in meeting all the requirements that specific field may demand. Therefore, PLA based nanocomposites are extensively investigated over the past few decades. PLA based nanocomposites include PLA based copolymers in nanometer size and nanocomposites with PLA or PLA copolymers as matrix and nanofillers as annexing agent. The small scale effect and surface effect of nanomaterials help improve the properties of PLA and make PLA based nanocomposites more popular compared with pure PLA materials. This review mainly introduces different kinds of PLA based nanocomposites in recent researches that have great potential to be used in biomedical fields including bone substitute and repair, tissue engineering, and drug delivery system.</jats:p>

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