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- Sébastien Duplessis
- Unité Mixte de Recherche 1136, Institut National de la Recherche Agronomique/Nancy Université, Interactions Arbres/Micro-organismes, Centre de Nancy, 54280 Champenoux, France;
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- Christina A. Cuomo
- Broad Institute of Massachusetts Institute of Technology and Harvard University, Cambridge, MA 02142;
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- Yao-Cheng Lin
- Department of Plant Systems Biology, VIB, B-9052 Ghent, Belgium;
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- Andrea Aerts
- US Department of Energy Joint Genome Institute, Walnut Creek, CA 94598;
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- Emilie Tisserant
- Unité Mixte de Recherche 1136, Institut National de la Recherche Agronomique/Nancy Université, Interactions Arbres/Micro-organismes, Centre de Nancy, 54280 Champenoux, France;
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- Claire Veneault-Fourrey
- Unité Mixte de Recherche 1136, Institut National de la Recherche Agronomique/Nancy Université, Interactions Arbres/Micro-organismes, Centre de Nancy, 54280 Champenoux, France;
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- David L. Joly
- Natural Resources Canada, Ste-Foy, QC, Canada G1V 4C7;
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- Stéphane Hacquard
- Unité Mixte de Recherche 1136, Institut National de la Recherche Agronomique/Nancy Université, Interactions Arbres/Micro-organismes, Centre de Nancy, 54280 Champenoux, France;
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- Joëlle Amselem
- Institut National de la Recherche Agronomique, Unité de Recherche Génomique Info, 78026 Versailles Cedex, France;
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- Brandi L. Cantarel
- Unité Mixte de Recherche 6098, Centre National de la Recherche Scientifique–Universités Aix-Marseille I and II, Marseille, France;
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- Readman Chiu
- Genome Sciences Centre, British Columbia Cancer Agency, Vancouver, BC, V5Z 4S6 Canada;
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- Pedro M. Coutinho
- Unité Mixte de Recherche 6098, Centre National de la Recherche Scientifique–Universités Aix-Marseille I and II, Marseille, France;
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- Nicolas Feau
- Natural Resources Canada, Ste-Foy, QC, Canada G1V 4C7;
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- Matthew Field
- Genome Sciences Centre, British Columbia Cancer Agency, Vancouver, BC, V5Z 4S6 Canada;
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- Pascal Frey
- Unité Mixte de Recherche 1136, Institut National de la Recherche Agronomique/Nancy Université, Interactions Arbres/Micro-organismes, Centre de Nancy, 54280 Champenoux, France;
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- Eric Gelhaye
- Unité Mixte de Recherche 1136, Institut National de la Recherche Agronomique/Nancy Université, Interactions Arbres/Micro-organismes, Centre de Nancy, 54280 Champenoux, France;
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- Jonathan Goldberg
- Broad Institute of Massachusetts Institute of Technology and Harvard University, Cambridge, MA 02142;
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- Manfred G. Grabherr
- Broad Institute of Massachusetts Institute of Technology and Harvard University, Cambridge, MA 02142;
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- Chinnappa D. Kodira
- Broad Institute of Massachusetts Institute of Technology and Harvard University, Cambridge, MA 02142;
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- Annegret Kohler
- Unité Mixte de Recherche 1136, Institut National de la Recherche Agronomique/Nancy Université, Interactions Arbres/Micro-organismes, Centre de Nancy, 54280 Champenoux, France;
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- Ursula Kües
- Division of Molecular Wood Biotechnology and Technical Mycology, Büsgen-Institute, University of Göttingen, Büsgenweg, 37077 Göttingen, Germany;
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- Erika A. Lindquist
- US Department of Energy Joint Genome Institute, Walnut Creek, CA 94598;
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- Susan M. Lucas
- US Department of Energy Joint Genome Institute, Walnut Creek, CA 94598;
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- Rohit Mago
- Commonwealth Scientific and Industrial Research Organization, Plant Industry, Canberra, ACT 2601, Australia;
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- Evan Mauceli
- Broad Institute of Massachusetts Institute of Technology and Harvard University, Cambridge, MA 02142;
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- Emmanuelle Morin
- Unité Mixte de Recherche 1136, Institut National de la Recherche Agronomique/Nancy Université, Interactions Arbres/Micro-organismes, Centre de Nancy, 54280 Champenoux, France;
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- Claude Murat
- Unité Mixte de Recherche 1136, Institut National de la Recherche Agronomique/Nancy Université, Interactions Arbres/Micro-organismes, Centre de Nancy, 54280 Champenoux, France;
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- Jasmyn L. Pangilinan
- US Department of Energy Joint Genome Institute, Walnut Creek, CA 94598;
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- Robert Park
- Plant Breeding Institute Cobbitty, University of Sydney, Camden, NSW 2570, Australia;
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- Matthew Pearson
- Broad Institute of Massachusetts Institute of Technology and Harvard University, Cambridge, MA 02142;
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- Hadi Quesneville
- Institut National de la Recherche Agronomique, Unité de Recherche Génomique Info, 78026 Versailles Cedex, France;
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- Nicolas Rouhier
- Unité Mixte de Recherche 1136, Institut National de la Recherche Agronomique/Nancy Université, Interactions Arbres/Micro-organismes, Centre de Nancy, 54280 Champenoux, France;
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- Sharadha Sakthikumar
- Broad Institute of Massachusetts Institute of Technology and Harvard University, Cambridge, MA 02142;
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- Asaf A. Salamov
- US Department of Energy Joint Genome Institute, Walnut Creek, CA 94598;
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- Jeremy Schmutz
- US Department of Energy Joint Genome Institute, Walnut Creek, CA 94598;
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- Benjamin Selles
- Unité Mixte de Recherche 1136, Institut National de la Recherche Agronomique/Nancy Université, Interactions Arbres/Micro-organismes, Centre de Nancy, 54280 Champenoux, France;
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- Harris Shapiro
- US Department of Energy Joint Genome Institute, Walnut Creek, CA 94598;
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- Philippe Tanguay
- Natural Resources Canada, Ste-Foy, QC, Canada G1V 4C7;
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- Gerald A. Tuskan
- US Department of Energy Joint Genome Institute, Walnut Creek, CA 94598;
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- Bernard Henrissat
- Unité Mixte de Recherche 6098, Centre National de la Recherche Scientifique–Universités Aix-Marseille I and II, Marseille, France;
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- Yves Van de Peer
- Department of Plant Systems Biology, VIB, B-9052 Ghent, Belgium;
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- Pierre Rouzé
- Department of Plant Systems Biology, VIB, B-9052 Ghent, Belgium;
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- Jeffrey G. Ellis
- Commonwealth Scientific and Industrial Research Organization, Plant Industry, Canberra, ACT 2601, Australia;
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- Peter N. Dodds
- Commonwealth Scientific and Industrial Research Organization, Plant Industry, Canberra, ACT 2601, Australia;
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- Jacqueline E. Schein
- Genome Sciences Centre, British Columbia Cancer Agency, Vancouver, BC, V5Z 4S6 Canada;
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- Shaobin Zhong
- Department of Plant Pathology, University of Minnesota, St. Paul, MN 55108; and
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- Richard C. Hamelin
- Natural Resources Canada, Ste-Foy, QC, Canada G1V 4C7;
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- Igor V. Grigoriev
- US Department of Energy Joint Genome Institute, Walnut Creek, CA 94598;
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- Les J. Szabo
- Department of Plant Pathology, University of Minnesota, St. Paul, MN 55108; and
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- Francis Martin
- Unité Mixte de Recherche 1136, Institut National de la Recherche Agronomique/Nancy Université, Interactions Arbres/Micro-organismes, Centre de Nancy, 54280 Champenoux, France;
説明
<jats:p> Rust fungi are some of the most devastating pathogens of crop plants. They are obligate biotrophs, which extract nutrients only from living plant tissues and cannot grow apart from their hosts. Their lifestyle has slowed the dissection of molecular mechanisms underlying host invasion and avoidance or suppression of plant innate immunity. We sequenced the 101-Mb genome of <jats:italic>Melampsora larici</jats:italic> - <jats:italic>populina</jats:italic> , the causal agent of poplar leaf rust, and the 89-Mb genome of <jats:italic>Puccinia graminis</jats:italic> f. sp. <jats:italic>tritici</jats:italic> , the causal agent of wheat and barley stem rust. We then compared the 16,399 predicted proteins of <jats:italic>M. larici-populina</jats:italic> with the 17,773 predicted proteins of <jats:italic>P. graminis</jats:italic> f. sp <jats:italic>tritici</jats:italic> . Genomic features related to their obligate biotrophic lifestyle include expanded lineage-specific gene families, a large repertoire of effector-like small secreted proteins, impaired nitrogen and sulfur assimilation pathways, and expanded families of amino acid and oligopeptide membrane transporters. The dramatic up-regulation of transcripts coding for small secreted proteins, secreted hydrolytic enzymes, and transporters <jats:italic>in planta</jats:italic> suggests that they play a role in host infection and nutrient acquisition. Some of these genomic hallmarks are mirrored in the genomes of other microbial eukaryotes that have independently evolved to infect plants, indicating convergent adaptation to a biotrophic existence inside plant cells. </jats:p>
収録刊行物
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- Proceedings of the National Academy of Sciences
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Proceedings of the National Academy of Sciences 108 (22), 9166-9171, 2011-05-02
Proceedings of the National Academy of Sciences