Lipid metabolism during lactation: a review of adipose tissue-liver interactions and the development of fatty liver

Richard G Vernon

doi:10.1017/s0022029905001299

Lipid metabolism during lactation: a review of adipose tissue-liver interactions and the development of fatty liver

DOI Web Site 被引用文献1件

Richard G Vernon

書誌事項

公開日: 2005-09-22

権利情報

https://www.cambridge.org/core/terms

DOI

10.1017/s0022029905001299

公開者: Cambridge University Press (CUP)

この論文をさがす

CiNii Books

説明

<jats:p>Fatty acids are the major source of energy for most tissues during periods of negative energy balance; however, fatty acids can, in some circumstances, have pathological effects. Fatty acids are stored as triacylglycerols (TAG), mostly in the various adipose tissue depots of the body. However, if blood unesterified fatty acid (NEFA) levels are elevated for prolonged periods, as may occur during lactation or obesity, TAG can accumulate in other tissues including liver and muscle cells (myocytes), and this can have pathological consequences such as the development of ketosis (Grummer, 1993; Drackley et al. 2001) or type 2 diabetes (Boden & Shulman, 2002; McGarry, 2002).</jats:p>