• S. INCERTI
    Université Bordeaux 1, CNRS/IN2P3, Centre d'Etudes Nucléaires de Bordeaux-Gradignan, CENBG, Chemin du solarium, BP 120, 33175 Gradignan, France
  • G. BALDACCHINO
    CEA Saclay, IRAMIS, UMR3299 CEA-CNRS SIS2M, Laboratoire de Radiolyse, F-91191 Gif-sur-Yvette Cedex, France
  • M. BERNAL
    Departamento de Física, Universidad Simon Bolívar, Venezuela
  • C. CHAMPION
    Université Paul Verlaine-Metz, Laboratoire de Physique, Moléculaire et des Collisions, 1 Boulevard Arago, Technopôle 2000, 57078 Metz, France
  • Z. FRANCIS
    IRSN, Institut de Radioprotection et de Sureté Nucléaire, BP17, 92262 Fontenay-aux-Roses, France
  • P. GUÈYE
    Hampton University, Physics Department, Hampton VA 23668, USA
  • A. MANTERO
    Université Bordeaux 1, CNRS/IN2P3, Centre d'Etudes Nucléaires de Bordeaux-Gradignan, CENBG, Chemin du solarium, BP 120, 33175 Gradignan, France
  • B. MASCIALINO
    Karolinska Institutet, Box 260, S-171-76, Stockholm, Sweden
  • P. MORETTO
    Université Bordeaux 1, CNRS/IN2P3, Centre d'Etudes Nucléaires de Bordeaux-Gradignan, CENBG, Chemin du solarium, BP 120, 33175 Gradignan, France
  • P. NIEMINEN
    ESA-ESTEC, 2200 AG Noordwijk, The Netherlands
  • C. VILLAGRASA
    IRSN, Institut de Radioprotection et de Sureté Nucléaire, BP17, 92262 Fontenay-aux-Roses, France
  • C. ZACHARATOU
    Niels Bohr Institute, Blegdamsvej 17, 2100 Copenhagen, Denmark

書誌事項

公開日
2010-06
DOI
  • 10.1142/s1793962310000122
公開者
World Scientific Pub Co Pte Lt

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説明

<jats:p> The Geant4-DNA project proposes to develop an open-source simulation software based and fully included in the general-purpose Geant4 Monte-Carlo simulation toolkit. The main objective of this software is to simulate biological damages induced by ionizing radiations at the cellular and sub-cellular scale. This project was originally initiated by the European Space Agency for the prediction of the deleterious effects of radiations that may affect astronauts during future long duration space exploration missions. In this paper, the Geant4-DNA collaboration presents an overview of the whole on-going project, including its most recent developments that are available in the Geant4 toolkit since December 2009 (release 9.3), as well as an illustration example simulating the direct irradiation of a biological chromatin fiber. Expected extensions involving several research domains, such as particle physics, chemistry and cellular and molecular biology, within a fully interdisciplinary activity of the Geant4 collaboration are also discussed. </jats:p>

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