Factors associated with increased frequency of HIV‐related oral candidiasis

DOI Web Site Web Site 被引用文献1件

書誌事項

公開日
1991-08
権利情報
  • http://onlinelibrary.wiley.com/termsAndConditions#vor
DOI
  • 10.1111/j.1600-0714.1991.tb00940.x
公開者
Wiley

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<jats:p>HIV‐related oral candidiasis was investigated in 71 HIV‐seropositive patients who received interviews, oral examinations and hematologic investigation. Diagnosis of candidiasis was based on clinical signs and examination of PAS‐stained smears. The frequency of candidiasis was 24/71 (34%). The clinical presentations were pseudomembranous 8 (11%), erythematous 14 (20%), angular cheilitis 3 (4%). Twenty‐six patients (37%) had candidiasis or were receiving antifungal treatment for recurrent pseudomembranous type. Twelve of 13 (92%) patients with AIDS and 14/58 (24%) without AIDS were affected. Bivariate analyses showed significant associations with AIDS, the use of zidovudine, low T4‐count, xerostomia: marital status (sometime married), restricted performance status and age of >35 yr. Multivariate logistic regression analysis showed that the presence of xerostomia was an independent and statistically significant predictor of HIV‐related oral candidiasis. T4‐count and restricted performance status were the second and third most important predictors.</jats:p>

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