Lack of Correlation between Results of ABO-Incompatible Living Kidney Transplantation and Anti-ABO Blood Type Antibody Titers under Our Current Immunosuppression
書誌事項
- 公開日
- 2005-10
- DOI
-
- 10.1097/01.tp.0000173647.43616.78
- 公開者
- Ovid Technologies (Wolters Kluwer Health)
この論文をさがす
説明
In this study, we examined the impact of preoperative anti-A/B antibody titers on the results of ABO-incompatible living kidney transplantation (LKT). In all, 167 recipients underwent ABO-incompatible LKT at our institution between 1989 and 2002. These patients were subdivided into those transplanted under cyclosporine with azathioprine or mizoribine (Group 1, n=78) and those transplanted under tacrolimus or mycophenolate mofetil (Group 2, n=89). Overall patient survival at 5 and 10 years was 93.8% and 88.0%, respectively. Overall graft survival at 5 and 10 years was 76.9% and 55.9%, respectively. Graft survival in the patients with anti-A/B IgG titers over 1:128 was significantly lower in group 1, whereas no significant correlation between the anti-A/B IgG titers and graft survival was found in group 2. In conclusion, no correlation between anti-A/B antibody titers and the results of ABO-incompatible LKT was seen after tacrolimus or mycophenolate mofetil application.
収録刊行物
-
- Transplantation
-
Transplantation 80 (7), 985-988, 2005-10
Ovid Technologies (Wolters Kluwer Health)