Resident memory CD8 <sup>+</sup> T cells in the upper respiratory tract prevent pulmonary influenza virus infection
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- Angela Pizzolla
- Department of Microbiology and Immunology, University of Melbourne, at Peter Doherty Institute for Infection and Immunity, Melbourne, Victoria 3000, Australia.
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- Thi H. O. Nguyen
- Department of Microbiology and Immunology, University of Melbourne, at Peter Doherty Institute for Infection and Immunity, Melbourne, Victoria 3000, Australia.
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- Jeffrey M. Smith
- Department of Microbiology and Immunology, University of Melbourne, at Peter Doherty Institute for Infection and Immunity, Melbourne, Victoria 3000, Australia.
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- Andrew G. Brooks
- Department of Microbiology and Immunology, University of Melbourne, at Peter Doherty Institute for Infection and Immunity, Melbourne, Victoria 3000, Australia.
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- Katherine Kedzierska
- Department of Microbiology and Immunology, University of Melbourne, at Peter Doherty Institute for Infection and Immunity, Melbourne, Victoria 3000, Australia.
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- William R. Heath
- Department of Microbiology and Immunology, University of Melbourne, at Peter Doherty Institute for Infection and Immunity, Melbourne, Victoria 3000, Australia.
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- Patrick C. Reading
- Department of Microbiology and Immunology, University of Melbourne, at Peter Doherty Institute for Infection and Immunity, Melbourne, Victoria 3000, Australia.
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- Linda M. Wakim
- Department of Microbiology and Immunology, University of Melbourne, at Peter Doherty Institute for Infection and Immunity, Melbourne, Victoria 3000, Australia.
抄録
<jats:p>Nasal tissue–resident memory T cells block influenza virus transmission to the lung, preventing severe pulmonary disease.</jats:p>
収録刊行物
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- Science Immunology
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Science Immunology 2 (12), eaam6970-, 2017-06-09
American Association for the Advancement of Science (AAAS)