Production of citric acid in continuous culture

書誌事項

公開日
1979-02
権利情報
  • http://onlinelibrary.wiley.com/termsAndConditions#vor
DOI
  • 10.1002/bit.260210214
公開者
Wiley

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説明

<jats:title>Abstract</jats:title><jats:p>Work has been carried out on the production of citric acid by <jats:italic>Aspergillus foetidus</jats:italic> in single‐stage continuous culture, operated under nitrogen‐limiting conditions at dilution rates between 0.04 to 0.21 hr<jats:sup>−1</jats:sup>. Citric acid concentration increased rapidly as the dilution rate decreased and appears to be critically dependent on the pH in the culture vessel and the nitrogen concentration in the feed. A mathematical model based on a distinction between basic cells, which require nitrogen but do not produce citric acid, and stroage cells, which accumulate carbon and simultaneously produce citric acid, is proposed.</jats:p>

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