Novel C-17-Heteroaryl Steroidal CYP17 Inhibitors/Antiandrogens: Synthesis, in Vitro Biological Activity, Pharmacokinetics, and Antitumor Activity in the LAPC4 Human Prostate Cancer Xenograft Model
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- Venkatesh D. Handratta
- Department of Pharmacology and Experimental Therapeutics, University of Maryland School of Medicine, Baltimore, 655 West Baltimore Street, Baltimore, Maryland 21201-1559
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- Tadas S. Vasaitis
- Department of Pharmacology and Experimental Therapeutics, University of Maryland School of Medicine, Baltimore, 655 West Baltimore Street, Baltimore, Maryland 21201-1559
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- Vincent C. O. Njar
- Department of Pharmacology and Experimental Therapeutics, University of Maryland School of Medicine, Baltimore, 655 West Baltimore Street, Baltimore, Maryland 21201-1559
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- Lalji K. Gediya
- Department of Pharmacology and Experimental Therapeutics, University of Maryland School of Medicine, Baltimore, 655 West Baltimore Street, Baltimore, Maryland 21201-1559
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- Ritesh Kataria
- Department of Pharmacology and Experimental Therapeutics, University of Maryland School of Medicine, Baltimore, 655 West Baltimore Street, Baltimore, Maryland 21201-1559
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- Pankaj Chopra
- Department of Pharmacology and Experimental Therapeutics, University of Maryland School of Medicine, Baltimore, 655 West Baltimore Street, Baltimore, Maryland 21201-1559
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- Donnell Newman
- Department of Pharmacology and Experimental Therapeutics, University of Maryland School of Medicine, Baltimore, 655 West Baltimore Street, Baltimore, Maryland 21201-1559
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- Rena Farquhar
- Department of Pharmacology and Experimental Therapeutics, University of Maryland School of Medicine, Baltimore, 655 West Baltimore Street, Baltimore, Maryland 21201-1559
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- Zhiyong Guo
- Department of Pharmacology and Experimental Therapeutics, University of Maryland School of Medicine, Baltimore, 655 West Baltimore Street, Baltimore, Maryland 21201-1559
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- Yun Qiu
- Department of Pharmacology and Experimental Therapeutics, University of Maryland School of Medicine, Baltimore, 655 West Baltimore Street, Baltimore, Maryland 21201-1559
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- Angela M. H. Brodie
- Department of Pharmacology and Experimental Therapeutics, University of Maryland School of Medicine, Baltimore, 655 West Baltimore Street, Baltimore, Maryland 21201-1559
収録刊行物
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- Journal of Medicinal Chemistry
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Journal of Medicinal Chemistry 48 (8), 2972-2984, 2005-03-25
American Chemical Society (ACS)