Infrequent Finding of Metallo-β-Lactamase VIM-2 in Carbapenem-Resistant Pseudomonas aeruginosa Strains from Croatia
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- Sanda Sardelic
- Clinical Institute for Microbiology, Split University Hospital, Split, Croatia
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- Branka Bedenic
- Clinical Institute for Clinical Microbiology, Zagreb University Hospital, Zagreb, Croatia
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- Céline Colinon-Dupuich
- Laboratory of Microbial Ecology, UMR 5557 Microbial Ecology, Université Lyon 1, CNRS, and VetAgro Sup Veterinary School, Lyon, France
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- Stjepan Orhanovic
- Department of Chemistry, Faculty of Science, University of Split, Split, Croatia
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- Zrinka Bosnjak
- Clinical Institute for Clinical Microbiology, Zagreb University Hospital, Zagreb, Croatia
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- Vanda Plecko
- Clinical Institute for Clinical Microbiology, Zagreb University Hospital, Zagreb, Croatia
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- Benoit Cournoyer
- Laboratory of Microbial Ecology, UMR 5557 Microbial Ecology, Université Lyon 1, CNRS, and VetAgro Sup Veterinary School, Lyon, France
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- Gian Maria Rossolini
- Department of Biotechnologies, University of Siena, and Microbiology and Virology Unit, Siena University Hospital, Siena, Italy
書誌事項
- 公開日
- 2012-05
- 権利情報
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- https://journals.asm.org/non-commercial-tdm-license
- DOI
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- 10.1128/aac.05212-11
- 公開者
- American Society for Microbiology
この論文をさがす
説明
<jats:title>ABSTRACT</jats:title> <jats:p> One hundred sixty-nine nonreplicate imipenem-resistant <jats:named-content xmlns:xlink="http://www.w3.org/1999/xlink" content-type="genus-species" xlink:type="simple">Pseudomonas aeruginosa</jats:named-content> strains isolated in a large hospital on the coastal region of Croatia were studied. The most active antibiotics were colistin and amikacin. Most of the isolates were multiresistant. The most prevalent serotype was O12, followed by O11. Six strains carried the <jats:italic>bla</jats:italic> <jats:sub>VIM-2</jats:sub> gene located in a novel class 1 integron composed in its variable part of the <jats:italic>bla</jats:italic> <jats:sub>VIM-2</jats:sub> - <jats:italic>bla</jats:italic> <jats:sub>oxa-10</jats:sub> -Δ <jats:italic>qacF-aacA4</jats:italic> genes. Metallo-β-lactamase-producing strains belonged to sequence types ST235 and ST111. </jats:p>
収録刊行物
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- Antimicrobial Agents and Chemotherapy
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Antimicrobial Agents and Chemotherapy 56 (5), 2746-2749, 2012-05
American Society for Microbiology
