Safety and Efficacy of Pulmonary Vein Antral Isolation in Patients With Obstructive Sleep Apnea

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  • Dimpi Patel
    From St David's Medical Center and Texas Cardiac Arrhythmia Center (D.P., P.M., L.D.B., P.V., R.H., J.S., J.G., D.S.C., J.Z., R.C., S.B., J.D.B., A.N.), Austin, Tex; Akron General Hospital (J.E.C., R.S.), Akron, Ohio; Stanford University (P.W., A.A.-A.), Palo Alto, Calif; Metro Health Hospital (W.R.L., K.Q.), Case Western Reserve, Cleveland, Ohio; California Pacific Medical Center (S.H., S.B.), San Francisco, Calif; Kansas University (D.L.), Lawrence, Kan; the University of Cincinnati (M.S., E.N.),...
  • Prasant Mohanty
    From St David's Medical Center and Texas Cardiac Arrhythmia Center (D.P., P.M., L.D.B., P.V., R.H., J.S., J.G., D.S.C., J.Z., R.C., S.B., J.D.B., A.N.), Austin, Tex; Akron General Hospital (J.E.C., R.S.), Akron, Ohio; Stanford University (P.W., A.A.-A.), Palo Alto, Calif; Metro Health Hospital (W.R.L., K.Q.), Case Western Reserve, Cleveland, Ohio; California Pacific Medical Center (S.H., S.B.), San Francisco, Calif; Kansas University (D.L.), Lawrence, Kan; the University of Cincinnati (M.S., E.N.),...
  • Luigi Di Biase
    From St David's Medical Center and Texas Cardiac Arrhythmia Center (D.P., P.M., L.D.B., P.V., R.H., J.S., J.G., D.S.C., J.Z., R.C., S.B., J.D.B., A.N.), Austin, Tex; Akron General Hospital (J.E.C., R.S.), Akron, Ohio; Stanford University (P.W., A.A.-A.), Palo Alto, Calif; Metro Health Hospital (W.R.L., K.Q.), Case Western Reserve, Cleveland, Ohio; California Pacific Medical Center (S.H., S.B.), San Francisco, Calif; Kansas University (D.L.), Lawrence, Kan; the University of Cincinnati (M.S., E.N.),...
  • Mazen Shaheen
    From St David's Medical Center and Texas Cardiac Arrhythmia Center (D.P., P.M., L.D.B., P.V., R.H., J.S., J.G., D.S.C., J.Z., R.C., S.B., J.D.B., A.N.), Austin, Tex; Akron General Hospital (J.E.C., R.S.), Akron, Ohio; Stanford University (P.W., A.A.-A.), Palo Alto, Calif; Metro Health Hospital (W.R.L., K.Q.), Case Western Reserve, Cleveland, Ohio; California Pacific Medical Center (S.H., S.B.), San Francisco, Calif; Kansas University (D.L.), Lawrence, Kan; the University of Cincinnati (M.S., E.N.),...
  • William R. Lewis
    From St David's Medical Center and Texas Cardiac Arrhythmia Center (D.P., P.M., L.D.B., P.V., R.H., J.S., J.G., D.S.C., J.Z., R.C., S.B., J.D.B., A.N.), Austin, Tex; Akron General Hospital (J.E.C., R.S.), Akron, Ohio; Stanford University (P.W., A.A.-A.), Palo Alto, Calif; Metro Health Hospital (W.R.L., K.Q.), Case Western Reserve, Cleveland, Ohio; California Pacific Medical Center (S.H., S.B.), San Francisco, Calif; Kansas University (D.L.), Lawrence, Kan; the University of Cincinnati (M.S., E.N.),...
  • Kara Quan
    From St David's Medical Center and Texas Cardiac Arrhythmia Center (D.P., P.M., L.D.B., P.V., R.H., J.S., J.G., D.S.C., J.Z., R.C., S.B., J.D.B., A.N.), Austin, Tex; Akron General Hospital (J.E.C., R.S.), Akron, Ohio; Stanford University (P.W., A.A.-A.), Palo Alto, Calif; Metro Health Hospital (W.R.L., K.Q.), Case Western Reserve, Cleveland, Ohio; California Pacific Medical Center (S.H., S.B.), San Francisco, Calif; Kansas University (D.L.), Lawrence, Kan; the University of Cincinnati (M.S., E.N.),...
  • Jennifer E. Cummings
    From St David's Medical Center and Texas Cardiac Arrhythmia Center (D.P., P.M., L.D.B., P.V., R.H., J.S., J.G., D.S.C., J.Z., R.C., S.B., J.D.B., A.N.), Austin, Tex; Akron General Hospital (J.E.C., R.S.), Akron, Ohio; Stanford University (P.W., A.A.-A.), Palo Alto, Calif; Metro Health Hospital (W.R.L., K.Q.), Case Western Reserve, Cleveland, Ohio; California Pacific Medical Center (S.H., S.B.), San Francisco, Calif; Kansas University (D.L.), Lawrence, Kan; the University of Cincinnati (M.S., E.N.),...
  • Paul Wang
    From St David's Medical Center and Texas Cardiac Arrhythmia Center (D.P., P.M., L.D.B., P.V., R.H., J.S., J.G., D.S.C., J.Z., R.C., S.B., J.D.B., A.N.), Austin, Tex; Akron General Hospital (J.E.C., R.S.), Akron, Ohio; Stanford University (P.W., A.A.-A.), Palo Alto, Calif; Metro Health Hospital (W.R.L., K.Q.), Case Western Reserve, Cleveland, Ohio; California Pacific Medical Center (S.H., S.B.), San Francisco, Calif; Kansas University (D.L.), Lawrence, Kan; the University of Cincinnati (M.S., E.N.),...
  • Amin Al-Ahmad
    From St David's Medical Center and Texas Cardiac Arrhythmia Center (D.P., P.M., L.D.B., P.V., R.H., J.S., J.G., D.S.C., J.Z., R.C., S.B., J.D.B., A.N.), Austin, Tex; Akron General Hospital (J.E.C., R.S.), Akron, Ohio; Stanford University (P.W., A.A.-A.), Palo Alto, Calif; Metro Health Hospital (W.R.L., K.Q.), Case Western Reserve, Cleveland, Ohio; California Pacific Medical Center (S.H., S.B.), San Francisco, Calif; Kansas University (D.L.), Lawrence, Kan; the University of Cincinnati (M.S., E.N.),...
  • Preeti Venkatraman
    From St David's Medical Center and Texas Cardiac Arrhythmia Center (D.P., P.M., L.D.B., P.V., R.H., J.S., J.G., D.S.C., J.Z., R.C., S.B., J.D.B., A.N.), Austin, Tex; Akron General Hospital (J.E.C., R.S.), Akron, Ohio; Stanford University (P.W., A.A.-A.), Palo Alto, Calif; Metro Health Hospital (W.R.L., K.Q.), Case Western Reserve, Cleveland, Ohio; California Pacific Medical Center (S.H., S.B.), San Francisco, Calif; Kansas University (D.L.), Lawrence, Kan; the University of Cincinnati (M.S., E.N.),...
  • Eyad Nashawati
    From St David's Medical Center and Texas Cardiac Arrhythmia Center (D.P., P.M., L.D.B., P.V., R.H., J.S., J.G., D.S.C., J.Z., R.C., S.B., J.D.B., A.N.), Austin, Tex; Akron General Hospital (J.E.C., R.S.), Akron, Ohio; Stanford University (P.W., A.A.-A.), Palo Alto, Calif; Metro Health Hospital (W.R.L., K.Q.), Case Western Reserve, Cleveland, Ohio; California Pacific Medical Center (S.H., S.B.), San Francisco, Calif; Kansas University (D.L.), Lawrence, Kan; the University of Cincinnati (M.S., E.N.),...
  • Dhanunjaya Lakkireddy
    From St David's Medical Center and Texas Cardiac Arrhythmia Center (D.P., P.M., L.D.B., P.V., R.H., J.S., J.G., D.S.C., J.Z., R.C., S.B., J.D.B., A.N.), Austin, Tex; Akron General Hospital (J.E.C., R.S.), Akron, Ohio; Stanford University (P.W., A.A.-A.), Palo Alto, Calif; Metro Health Hospital (W.R.L., K.Q.), Case Western Reserve, Cleveland, Ohio; California Pacific Medical Center (S.H., S.B.), San Francisco, Calif; Kansas University (D.L.), Lawrence, Kan; the University of Cincinnati (M.S., E.N.),...
  • Robert Schweikert
    From St David's Medical Center and Texas Cardiac Arrhythmia Center (D.P., P.M., L.D.B., P.V., R.H., J.S., J.G., D.S.C., J.Z., R.C., S.B., J.D.B., A.N.), Austin, Tex; Akron General Hospital (J.E.C., R.S.), Akron, Ohio; Stanford University (P.W., A.A.-A.), Palo Alto, Calif; Metro Health Hospital (W.R.L., K.Q.), Case Western Reserve, Cleveland, Ohio; California Pacific Medical Center (S.H., S.B.), San Francisco, Calif; Kansas University (D.L.), Lawrence, Kan; the University of Cincinnati (M.S., E.N.),...
  • Rodney Horton
    From St David's Medical Center and Texas Cardiac Arrhythmia Center (D.P., P.M., L.D.B., P.V., R.H., J.S., J.G., D.S.C., J.Z., R.C., S.B., J.D.B., A.N.), Austin, Tex; Akron General Hospital (J.E.C., R.S.), Akron, Ohio; Stanford University (P.W., A.A.-A.), Palo Alto, Calif; Metro Health Hospital (W.R.L., K.Q.), Case Western Reserve, Cleveland, Ohio; California Pacific Medical Center (S.H., S.B.), San Francisco, Calif; Kansas University (D.L.), Lawrence, Kan; the University of Cincinnati (M.S., E.N.),...
  • Javier Sanchez
    From St David's Medical Center and Texas Cardiac Arrhythmia Center (D.P., P.M., L.D.B., P.V., R.H., J.S., J.G., D.S.C., J.Z., R.C., S.B., J.D.B., A.N.), Austin, Tex; Akron General Hospital (J.E.C., R.S.), Akron, Ohio; Stanford University (P.W., A.A.-A.), Palo Alto, Calif; Metro Health Hospital (W.R.L., K.Q.), Case Western Reserve, Cleveland, Ohio; California Pacific Medical Center (S.H., S.B.), San Francisco, Calif; Kansas University (D.L.), Lawrence, Kan; the University of Cincinnati (M.S., E.N.),...
  • Joseph Gallinghouse
    From St David's Medical Center and Texas Cardiac Arrhythmia Center (D.P., P.M., L.D.B., P.V., R.H., J.S., J.G., D.S.C., J.Z., R.C., S.B., J.D.B., A.N.), Austin, Tex; Akron General Hospital (J.E.C., R.S.), Akron, Ohio; Stanford University (P.W., A.A.-A.), Palo Alto, Calif; Metro Health Hospital (W.R.L., K.Q.), Case Western Reserve, Cleveland, Ohio; California Pacific Medical Center (S.H., S.B.), San Francisco, Calif; Kansas University (D.L.), Lawrence, Kan; the University of Cincinnati (M.S., E.N.),...
  • Steven Hao
    From St David's Medical Center and Texas Cardiac Arrhythmia Center (D.P., P.M., L.D.B., P.V., R.H., J.S., J.G., D.S.C., J.Z., R.C., S.B., J.D.B., A.N.), Austin, Tex; Akron General Hospital (J.E.C., R.S.), Akron, Ohio; Stanford University (P.W., A.A.-A.), Palo Alto, Calif; Metro Health Hospital (W.R.L., K.Q.), Case Western Reserve, Cleveland, Ohio; California Pacific Medical Center (S.H., S.B.), San Francisco, Calif; Kansas University (D.L.), Lawrence, Kan; the University of Cincinnati (M.S., E.N.),...
  • Salwa Beheiry
    From St David's Medical Center and Texas Cardiac Arrhythmia Center (D.P., P.M., L.D.B., P.V., R.H., J.S., J.G., D.S.C., J.Z., R.C., S.B., J.D.B., A.N.), Austin, Tex; Akron General Hospital (J.E.C., R.S.), Akron, Ohio; Stanford University (P.W., A.A.-A.), Palo Alto, Calif; Metro Health Hospital (W.R.L., K.Q.), Case Western Reserve, Cleveland, Ohio; California Pacific Medical Center (S.H., S.B.), San Francisco, Calif; Kansas University (D.L.), Lawrence, Kan; the University of Cincinnati (M.S., E.N.),...
  • Deb S. Cardinal
    From St David's Medical Center and Texas Cardiac Arrhythmia Center (D.P., P.M., L.D.B., P.V., R.H., J.S., J.G., D.S.C., J.Z., R.C., S.B., J.D.B., A.N.), Austin, Tex; Akron General Hospital (J.E.C., R.S.), Akron, Ohio; Stanford University (P.W., A.A.-A.), Palo Alto, Calif; Metro Health Hospital (W.R.L., K.Q.), Case Western Reserve, Cleveland, Ohio; California Pacific Medical Center (S.H., S.B.), San Francisco, Calif; Kansas University (D.L.), Lawrence, Kan; the University of Cincinnati (M.S., E.N.),...
  • Jason Zagrodzky
    From St David's Medical Center and Texas Cardiac Arrhythmia Center (D.P., P.M., L.D.B., P.V., R.H., J.S., J.G., D.S.C., J.Z., R.C., S.B., J.D.B., A.N.), Austin, Tex; Akron General Hospital (J.E.C., R.S.), Akron, Ohio; Stanford University (P.W., A.A.-A.), Palo Alto, Calif; Metro Health Hospital (W.R.L., K.Q.), Case Western Reserve, Cleveland, Ohio; California Pacific Medical Center (S.H., S.B.), San Francisco, Calif; Kansas University (D.L.), Lawrence, Kan; the University of Cincinnati (M.S., E.N.),...
  • Robert Canby
    From St David's Medical Center and Texas Cardiac Arrhythmia Center (D.P., P.M., L.D.B., P.V., R.H., J.S., J.G., D.S.C., J.Z., R.C., S.B., J.D.B., A.N.), Austin, Tex; Akron General Hospital (J.E.C., R.S.), Akron, Ohio; Stanford University (P.W., A.A.-A.), Palo Alto, Calif; Metro Health Hospital (W.R.L., K.Q.), Case Western Reserve, Cleveland, Ohio; California Pacific Medical Center (S.H., S.B.), San Francisco, Calif; Kansas University (D.L.), Lawrence, Kan; the University of Cincinnati (M.S., E.N.),...
  • Shane Bailey
    From St David's Medical Center and Texas Cardiac Arrhythmia Center (D.P., P.M., L.D.B., P.V., R.H., J.S., J.G., D.S.C., J.Z., R.C., S.B., J.D.B., A.N.), Austin, Tex; Akron General Hospital (J.E.C., R.S.), Akron, Ohio; Stanford University (P.W., A.A.-A.), Palo Alto, Calif; Metro Health Hospital (W.R.L., K.Q.), Case Western Reserve, Cleveland, Ohio; California Pacific Medical Center (S.H., S.B.), San Francisco, Calif; Kansas University (D.L.), Lawrence, Kan; the University of Cincinnati (M.S., E.N.),...
  • J. David Burkhardt
    From St David's Medical Center and Texas Cardiac Arrhythmia Center (D.P., P.M., L.D.B., P.V., R.H., J.S., J.G., D.S.C., J.Z., R.C., S.B., J.D.B., A.N.), Austin, Tex; Akron General Hospital (J.E.C., R.S.), Akron, Ohio; Stanford University (P.W., A.A.-A.), Palo Alto, Calif; Metro Health Hospital (W.R.L., K.Q.), Case Western Reserve, Cleveland, Ohio; California Pacific Medical Center (S.H., S.B.), San Francisco, Calif; Kansas University (D.L.), Lawrence, Kan; the University of Cincinnati (M.S., E.N.),...
  • Andrea Natale
    From St David's Medical Center and Texas Cardiac Arrhythmia Center (D.P., P.M., L.D.B., P.V., R.H., J.S., J.G., D.S.C., J.Z., R.C., S.B., J.D.B., A.N.), Austin, Tex; Akron General Hospital (J.E.C., R.S.), Akron, Ohio; Stanford University (P.W., A.A.-A.), Palo Alto, Calif; Metro Health Hospital (W.R.L., K.Q.), Case Western Reserve, Cleveland, Ohio; California Pacific Medical Center (S.H., S.B.), San Francisco, Calif; Kansas University (D.L.), Lawrence, Kan; the University of Cincinnati (M.S., E.N.),...

書誌事項

タイトル別名
  • The Impact of Continuous Positive Airway Pressure

抄録

<jats:sec> <jats:title>Background—</jats:title> <jats:p>Obstructive sleep apnea (OSA) may be associated with pulmonary vein antrum isolation (PVAI) failure. The aim of the present study was to investigate if treatment with continuous positive airway pressure (CPAP) improved PVAI success rates.</jats:p> </jats:sec> <jats:sec> <jats:title>Methods and Results—</jats:title> <jats:p> From January 2004 to December 2007, 3000 consecutive patients underwent PVAI. Patients were screened for OSA and CPAP use. Six hundred forty (21.3%) patients had OSA. Patients with OSA had more procedural failures ( <jats:italic>P</jats:italic> =0.024) and hematomas ( <jats:italic>P</jats:italic> <0.001). Eight percent of the non-OSA paroxysmal atrial fibrillation patients had nonpulmonary vein antrum triggers (non-PV triggers) and posterior wall firing versus 20% of the OSA group ( <jats:italic>P</jats:italic> <0.001). Nineteen percent of the non-OSA nonparoxysmal atrial fibrillation population had non-PV triggers versus 31% in the OSA group ( <jats:italic>P</jats:italic> =0.001). At the end of the follow-up period (32±14 months), 79% of the non-CPAP and 68% of the CPAP group were free of atrial fibrillation ( <jats:italic>P</jats:italic> =0.003). Not using CPAP in addition to having non-PV triggers strongly predicted procedural failure (hazard ratio, 8.81; <jats:italic>P</jats:italic> <0.001). </jats:p> </jats:sec> <jats:sec> <jats:title>Conclusions—</jats:title> <jats:p>OSA was an independent predictor for PVAI failure. Treatment with CPAP improved PVAI success rates. Patients not treated with CPAP in addition to having higher prevalence of non-PV triggers were 8 times more likely to fail the procedure.</jats:p> </jats:sec>

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