Genome-wide association study of offspring birth weight in 86 577 women identifies five novel loci and highlights maternal genetic effects that are independent of fetal genetics
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- Robin N Beaumont
- Institute of Biomedical and Clinical Science, University of Exeter Medical School, University of Exeter, Royal Devon and Exeter Hospital, Exeter EX2 5DW, UK,
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- Nicole M Warrington
- Translational Research Institute, University of Queensland Diamantina Institute, Brisbane, QLD, Australia,
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- Alana Cavadino
- Centre for Environmental and Preventive Medicine, Wolfson Institute of Preventive Medicine, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, London, UK,
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- Jessica Tyrrell
- Institute of Biomedical and Clinical Science, University of Exeter Medical School, University of Exeter, Royal Devon and Exeter Hospital, Exeter EX2 5DW, UK,
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- Michael Nodzenski
- Department of Preventive Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, USA,
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- Momoko Horikoshi
- Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Oxford, UK,
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- Frank Geller
- Department of Epidemiology Research, Statens Serum Institut, Copenhagen, Denmark,
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- Ronny Myhre
- Division of Epidemiology, Department of Genes and Environment, Norwegian Institute of Public Health, Oslo, Norway,
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- Rebecca C Richmond
- Medical Research Council Integrative Epidemiology Unit at the University of Bristol, Oakfield House, Oakfield Grove, Bristol BS8 2BN, UK,
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- Lavinia Paternoster
- Medical Research Council Integrative Epidemiology Unit at the University of Bristol, Oakfield House, Oakfield Grove, Bristol BS8 2BN, UK,
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- Jonathan P Bradfield
- Center for Applied Genomics, The Children’s Hospital of Philadelphia, Philadelphia, PA, USA,
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- Eskil Kreiner-Møller
- Copenhagen Prospective Studies on Asthma in Childhood (COPSAC), Faculty of Health Sciences, University of Copenhagen, Copenhagen, Denmark,
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- Ville Huikari
- Institute of Health Sciences, University of Oulu, Oulu, Finland,
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- Sarah Metrustry
- Department of Twin Research, King's College London, St. Thomas' Hospital, London, UK,
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- Kathryn L Lunetta
- Department of Biostatistics, Boston University School of Public Health, Boston, MA, USA,
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- Jodie N Painter
- QIMR Berghofer Medical Research Institute, Royal Brisbane Hospital, Herston, QLD 4029, Australia,
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- Jouke-Jan Hottenga
- EMGO Institute for Health and Care Research, VU University Medical Center, Amsterdam, The Netherlands,
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- Catherine Allard
- Centre de Recherche du Centre Hospitalier Universitaire de Sherbrooke, Sherbrooke, QC, Canada,
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- Sheila J Barton
- Medical Research Council Lifecourse Epidemiology Unit, University of Southampton, Southampton, UK,
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- Ana Espinosa
- Pompeu Fabra University (UPF), Barcelona, Spain,
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- Julie A Marsh
- Division of Obstetrics and Gynaecology, The University of Western Australia, Perth, Australia,
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- Catherine Potter
- Institute of Genetic Medicine, Newcastle University, Central Parkway, Newcastle upon Tyne NE1 3BZ, UK,
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- Ge Zhang
- Human Genetics Division, Cincinnati Children’s Hospital Medical Center, Cincinnati, OH, USA,
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- Wei Ang
- Division of Obstetrics and Gynaecology, The University of Western Australia, Perth, Australia,
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- Diane J Berry
- Population, Policy and Practice, UCL Great Ormond Street Institute of Child Health, University College London, London, UK,
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- Luigi Bouchard
- Centre de Recherche du Centre Hospitalier Universitaire de Sherbrooke, Sherbrooke, QC, Canada,
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- Shikta Das
- Population, Policy and Practice, UCL Great Ormond Street Institute of Child Health, University College London, London, UK,
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- Hakon Hakonarson
- Center for Applied Genomics, The Children’s Hospital of Philadelphia, Philadelphia, PA, USA,
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- Jani Heikkinen
- FIMM Institute for Molecular Medicine Finland, Helsinki University, Helsinki FI-00014, Finland,
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- Øyvind Helgeland
- Department of Clinical Science, KG Jebsen Center for Diabetes Research, University of Bergen, Bergen, Norway,
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- Berthold Hocher
- The First Affiliated Hospital of Jinan University, Guangzhou 510630, China,
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- Albert Hofman
- Department of Epidemiology, Erasmus MC, University Medical Center Rotterdam, 3000 CA Rotterdam, The Netherlands,
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- Hazel M Inskip
- Medical Research Council Lifecourse Epidemiology Unit, University of Southampton, Southampton, UK,
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- Samuel E Jones
- Institute of Biomedical and Clinical Science, University of Exeter Medical School, University of Exeter, Royal Devon and Exeter Hospital, Exeter EX2 5DW, UK,
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- Manolis Kogevinas
- Pompeu Fabra University (UPF), Barcelona, Spain,
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- Penelope A Lind
- QIMR Berghofer Medical Research Institute, Royal Brisbane Hospital, Herston, QLD 4029, Australia,
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- Letizia Marullo
- Genetic Section, Department of Life Sciences and Biotechnology, University of Ferrara, Ferrara, Italy,
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- Sarah E Medland
- QIMR Berghofer Medical Research Institute, Royal Brisbane Hospital, Herston, QLD 4029, Australia,
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- Anna Murray
- Institute of Biomedical and Clinical Science, University of Exeter Medical School, University of Exeter, Royal Devon and Exeter Hospital, Exeter EX2 5DW, UK,
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- Jeffrey C Murray
- Department of Pediatrics, University of Iowa, Iowa City, IA, USA,
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- Pål R Njølstad
- Department of Clinical Science, KG Jebsen Center for Diabetes Research, University of Bergen, Bergen, Norway,
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- Ellen A Nohr
- Research Unit of Obstetrics & Gynecology, Institute of Clinical Research, University of Southern Denmark, Odense, Denmark,
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- Christoph Reichetzeder
- Institute of Nutritional Science, University of Potsdam, Potsdam, Germany,
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- Susan M Ring
- Medical Research Council Integrative Epidemiology Unit at the University of Bristol, Oakfield House, Oakfield Grove, Bristol BS8 2BN, UK,
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- Katherine S Ruth
- Institute of Biomedical and Clinical Science, University of Exeter Medical School, University of Exeter, Royal Devon and Exeter Hospital, Exeter EX2 5DW, UK,
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- Loreto Santa-Marina
- ISGlobal, Centre for Research in Environmental Epidemiology (CREAL), Barcelona, Spain,
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- Denise M Scholtens
- Department of Preventive Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, USA,
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- Sylvain Sebert
- Institute of Health Sciences, University of Oulu, Oulu, Finland,
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- Verena Sengpiel
- Department of Obstetrics and Gynecology, Sahlgrenska Academy, Sahgrenska University Hospital, Gothenburg, Sweden,
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- Marcus A Tuke
- Institute of Biomedical and Clinical Science, University of Exeter Medical School, University of Exeter, Royal Devon and Exeter Hospital, Exeter EX2 5DW, UK,
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- Marc Vaudel
- Department of Clinical Science, KG Jebsen Center for Diabetes Research, University of Bergen, Bergen, Norway,
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- Michael N Weedon
- Institute of Biomedical and Clinical Science, University of Exeter Medical School, University of Exeter, Royal Devon and Exeter Hospital, Exeter EX2 5DW, UK,
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- Gonneke Willemsen
- EMGO Institute for Health and Care Research, VU University Medical Center, Amsterdam, The Netherlands,
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- Andrew R Wood
- Institute of Biomedical and Clinical Science, University of Exeter Medical School, University of Exeter, Royal Devon and Exeter Hospital, Exeter EX2 5DW, UK,
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- Hanieh Yaghootkar
- Institute of Biomedical and Clinical Science, University of Exeter Medical School, University of Exeter, Royal Devon and Exeter Hospital, Exeter EX2 5DW, UK,
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- Louis J Muglia
- Center for Prevention of Preterm Birth, Perinatal Institute, Cincinnati Children's Hospital Medical Center, OH, USA,
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- Meike Bartels
- EMGO Institute for Health and Care Research, VU University Medical Center, Amsterdam, The Netherlands,
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- Caroline L Relton
- Medical Research Council Integrative Epidemiology Unit at the University of Bristol, Oakfield House, Oakfield Grove, Bristol BS8 2BN, UK,
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- Craig E Pennell
- Division of Obstetrics and Gynaecology, The University of Western Australia, Perth, Australia,
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- Leda Chatzi
- Department of Social Medicine, University of Crete, Crete, Greece,
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- Xavier Estivill
- Pompeu Fabra University (UPF), Barcelona, Spain,
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- John W Holloway
- Human Development & Health, Faculty of Medicine, University of Southampton, Southampton, UK,
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- Dorret I Boomsma
- EMGO Institute for Health and Care Research, VU University Medical Center, Amsterdam, The Netherlands,
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- Grant W Montgomery
- QIMR Berghofer Medical Research Institute, Royal Brisbane Hospital, Herston, QLD 4029, Australia,
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- Joanne M Murabito
- Framingham Heart Study, Framingham, MA, USA,
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- Tim D Spector
- Department of Twin Research, King's College London, St. Thomas' Hospital, London, UK,
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- Christine Power
- Population, Policy and Practice, UCL Great Ormond Street Institute of Child Health, University College London, London, UK,
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- Marjo-Ritta Järvelin
- Institute of Health Sciences, University of Oulu, Oulu, Finland,
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- Hans Bisgaard
- Copenhagen Prospective Studies on Asthma in Childhood (COPSAC), Faculty of Health Sciences, University of Copenhagen, Copenhagen, Denmark,
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- Struan F A Grant
- Center for Applied Genomics, The Children’s Hospital of Philadelphia, Philadelphia, PA, USA,
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- Thorkild I A Sørensen
- Medical Research Council Integrative Epidemiology Unit at the University of Bristol, Oakfield House, Oakfield Grove, Bristol BS8 2BN, UK,
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- Vincent W Jaddoe
- The Generation R Study Group, Erasmus MC, University Medical Center Rotterdam, 3000 CA Rotterdam, The Netherlands,
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- Bo Jacobsson
- Division of Epidemiology, Department of Genes and Environment, Norwegian Institute of Public Health, Oslo, Norway,
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- Mads Melbye
- Department of Epidemiology Research, Statens Serum Institut, Copenhagen, Denmark,
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- Mark I McCarthy
- Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Oxford, UK,
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- Andrew T Hattersley
- Institute of Biomedical and Clinical Science, University of Exeter Medical School, University of Exeter, Royal Devon and Exeter Hospital, Exeter EX2 5DW, UK,
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- M Geoffrey Hayes
- Division of Endocrinology, Metabolism and Molecular Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, USA,
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- Timothy M Frayling
- Institute of Biomedical and Clinical Science, University of Exeter Medical School, University of Exeter, Royal Devon and Exeter Hospital, Exeter EX2 5DW, UK,
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- Marie-France Hivert
- Department of Population Medicine, Harvard Pilgrim Health Care Institute, Harvard Medical School, Boston, MA, USA,
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- Janine F Felix
- The Generation R Study Group, Erasmus MC, University Medical Center Rotterdam, 3000 CA Rotterdam, The Netherlands,
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- Elina Hyppönen
- Population, Policy and Practice, UCL Great Ormond Street Institute of Child Health, University College London, London, UK,
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- William L Lowe
- Division of Endocrinology, Metabolism and Molecular Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, USA,
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- David M Evans
- Translational Research Institute, University of Queensland Diamantina Institute, Brisbane, QLD, Australia,
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- Debbie A Lawlor
- Medical Research Council Integrative Epidemiology Unit at the University of Bristol, Oakfield House, Oakfield Grove, Bristol BS8 2BN, UK,
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- Bjarke Feenstra
- Department of Epidemiology Research, Statens Serum Institut, Copenhagen, Denmark,
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- Rachel M Freathy
- Institute of Biomedical and Clinical Science, University of Exeter Medical School, University of Exeter, Royal Devon and Exeter Hospital, Exeter EX2 5DW, UK,
収録刊行物
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- Human Molecular Genetics
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Human Molecular Genetics 27 (4), 742-756, 2018-01-03
Oxford University Press (OUP)