Preparation of poly(glycolic acid) bonded fiber structures for cell attachment and transplantation

書誌事項

公開日
1993-02
権利情報
  • http://onlinelibrary.wiley.com/termsAndConditions#vor
DOI
  • 10.1002/jbm.820270207
公開者
Wiley

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説明

<jats:title>Abstract</jats:title><jats:p>A novel method was developed to prepare threedimensional structures with desired shapes used as templates for cell transplantation. The produced biomaterials are highly porous with large surface/volume and provide the necessary space for attachment and proliferation of the transplanted cells. The processing technique calls for the formation of a composite material with nonbonded fibers embedded in a matrix followed by thermal treatment and the selective dissolution of the matrix. To evaluate the technique, poly(glycolic acid) (PGA) fiber meshes were bonded using poly(<jats:sc>L</jats:sc>‐lactic acid) (PLLA) as a matrix. The bonded structures were highly porous with values of porosity up to 0.81 and area/volume ratios as high as 0.05 μm<jats:sup>−1</jats:sup>. © 1993 John Wiley & Sons, Inc.</jats:p>

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