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- Romaina Iqbal
- From the Population Health Research Institute (R.I., S.A., S.O., S.I., X.Z., S.R., S.Y.), Michael DeGroote School of Medicine, McMaster University and Hamilton Health Sciences, Hamilton, Ontario, Canada; Department of Community Health Sciences and Medicine (R.I.), The Aga Khan University, Karachi, Pakistan; Boehringer Ingelheim (S.O.), Burlington, Ontario, Canada; University of Zimbabwe (J.C.), Mount Pleasant, Harare, Zimbabwe; Sultan Qaboos University (A.A.-H.), Muscat, Oman; and Hungarian...
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- Sonia Anand
- From the Population Health Research Institute (R.I., S.A., S.O., S.I., X.Z., S.R., S.Y.), Michael DeGroote School of Medicine, McMaster University and Hamilton Health Sciences, Hamilton, Ontario, Canada; Department of Community Health Sciences and Medicine (R.I.), The Aga Khan University, Karachi, Pakistan; Boehringer Ingelheim (S.O.), Burlington, Ontario, Canada; University of Zimbabwe (J.C.), Mount Pleasant, Harare, Zimbabwe; Sultan Qaboos University (A.A.-H.), Muscat, Oman; and Hungarian...
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- Stephanie Ounpuu
- From the Population Health Research Institute (R.I., S.A., S.O., S.I., X.Z., S.R., S.Y.), Michael DeGroote School of Medicine, McMaster University and Hamilton Health Sciences, Hamilton, Ontario, Canada; Department of Community Health Sciences and Medicine (R.I.), The Aga Khan University, Karachi, Pakistan; Boehringer Ingelheim (S.O.), Burlington, Ontario, Canada; University of Zimbabwe (J.C.), Mount Pleasant, Harare, Zimbabwe; Sultan Qaboos University (A.A.-H.), Muscat, Oman; and Hungarian...
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- Shofiqul Islam
- From the Population Health Research Institute (R.I., S.A., S.O., S.I., X.Z., S.R., S.Y.), Michael DeGroote School of Medicine, McMaster University and Hamilton Health Sciences, Hamilton, Ontario, Canada; Department of Community Health Sciences and Medicine (R.I.), The Aga Khan University, Karachi, Pakistan; Boehringer Ingelheim (S.O.), Burlington, Ontario, Canada; University of Zimbabwe (J.C.), Mount Pleasant, Harare, Zimbabwe; Sultan Qaboos University (A.A.-H.), Muscat, Oman; and Hungarian...
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- Xiaohe Zhang
- From the Population Health Research Institute (R.I., S.A., S.O., S.I., X.Z., S.R., S.Y.), Michael DeGroote School of Medicine, McMaster University and Hamilton Health Sciences, Hamilton, Ontario, Canada; Department of Community Health Sciences and Medicine (R.I.), The Aga Khan University, Karachi, Pakistan; Boehringer Ingelheim (S.O.), Burlington, Ontario, Canada; University of Zimbabwe (J.C.), Mount Pleasant, Harare, Zimbabwe; Sultan Qaboos University (A.A.-H.), Muscat, Oman; and Hungarian...
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- Sumathy Rangarajan
- From the Population Health Research Institute (R.I., S.A., S.O., S.I., X.Z., S.R., S.Y.), Michael DeGroote School of Medicine, McMaster University and Hamilton Health Sciences, Hamilton, Ontario, Canada; Department of Community Health Sciences and Medicine (R.I.), The Aga Khan University, Karachi, Pakistan; Boehringer Ingelheim (S.O.), Burlington, Ontario, Canada; University of Zimbabwe (J.C.), Mount Pleasant, Harare, Zimbabwe; Sultan Qaboos University (A.A.-H.), Muscat, Oman; and Hungarian...
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- Jephat Chifamba
- From the Population Health Research Institute (R.I., S.A., S.O., S.I., X.Z., S.R., S.Y.), Michael DeGroote School of Medicine, McMaster University and Hamilton Health Sciences, Hamilton, Ontario, Canada; Department of Community Health Sciences and Medicine (R.I.), The Aga Khan University, Karachi, Pakistan; Boehringer Ingelheim (S.O.), Burlington, Ontario, Canada; University of Zimbabwe (J.C.), Mount Pleasant, Harare, Zimbabwe; Sultan Qaboos University (A.A.-H.), Muscat, Oman; and Hungarian...
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- Ali Al-Hinai
- From the Population Health Research Institute (R.I., S.A., S.O., S.I., X.Z., S.R., S.Y.), Michael DeGroote School of Medicine, McMaster University and Hamilton Health Sciences, Hamilton, Ontario, Canada; Department of Community Health Sciences and Medicine (R.I.), The Aga Khan University, Karachi, Pakistan; Boehringer Ingelheim (S.O.), Burlington, Ontario, Canada; University of Zimbabwe (J.C.), Mount Pleasant, Harare, Zimbabwe; Sultan Qaboos University (A.A.-H.), Muscat, Oman; and Hungarian...
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- Matyas Keltai
- From the Population Health Research Institute (R.I., S.A., S.O., S.I., X.Z., S.R., S.Y.), Michael DeGroote School of Medicine, McMaster University and Hamilton Health Sciences, Hamilton, Ontario, Canada; Department of Community Health Sciences and Medicine (R.I.), The Aga Khan University, Karachi, Pakistan; Boehringer Ingelheim (S.O.), Burlington, Ontario, Canada; University of Zimbabwe (J.C.), Mount Pleasant, Harare, Zimbabwe; Sultan Qaboos University (A.A.-H.), Muscat, Oman; and Hungarian...
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- Salim Yusuf
- From the Population Health Research Institute (R.I., S.A., S.O., S.I., X.Z., S.R., S.Y.), Michael DeGroote School of Medicine, McMaster University and Hamilton Health Sciences, Hamilton, Ontario, Canada; Department of Community Health Sciences and Medicine (R.I.), The Aga Khan University, Karachi, Pakistan; Boehringer Ingelheim (S.O.), Burlington, Ontario, Canada; University of Zimbabwe (J.C.), Mount Pleasant, Harare, Zimbabwe; Sultan Qaboos University (A.A.-H.), Muscat, Oman; and Hungarian...
書誌事項
- タイトル別名
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- Results of the INTERHEART Study
抄録
<jats:p> <jats:bold> <jats:italic>Background—</jats:italic> </jats:bold> Diet is a major modifiable risk factor for cardiovascular disease, but it varies markedly in different regions of the world. The objectives of the present study were to assess the association between dietary patterns and acute myocardial infarction (AMI) globally. </jats:p> <jats:p> <jats:bold> <jats:italic>Methods and Results—</jats:italic> </jats:bold> INTERHEART is a standardized case-control study involving participants from 52 countries. The present analysis included 5761 cases and 10 646 control subjects. We identified 3 major dietary patterns using factor analysis: Oriental (high intake of tofu and soy and other sauces), Western (high in fried foods, salty snacks, eggs, and meat), and prudent (high in fruit and vegetables). We observed an inverse association between the prudent pattern and AMI, with higher levels being protective. Compared with the first quartile, the adjusted ORs were 0.78 (95% CI 0.69 to 0.88) for the second quartile, 0.66 (95% CI 0.59 to 0.75) for the third, and 0.70 (95% CI 0.61 to 0.80) for the fourth ( <jats:italic>P</jats:italic> for trend <0.001). The Western pattern showed a U-shaped association with AMI (compared with the first quartile, the adjusted OR for the second quartile was 0.87 [95% CI 0.78 to 0.98], whereas it was 1.12 [95% CI 1.00 to 1.25] for the third quartile and 1.35 [95% CI 1.21 to 1.51] for the fourth quartile; <jats:italic>P</jats:italic> for trend <0.001), but the Oriental pattern demonstrated no relationship with AMI. Compared with the first quartile, the OR of a dietary risk score derived from meat, salty snacks, fried foods, fruits, green leafy vegetables, cooked vegetables, and other raw vegetables (higher score indicating a poorer diet) increased with each quartile: second quartile 1.29 (95% CI 1.17 to 1.42), third quartile 1.67 (95% CI 1.51 to 1.83), and fourth quartile 1.92 (95% CI 1.74 to 2.11; <jats:italic>P</jats:italic> for trend <0.001). The adjusted population-attributable risk of AMI for the top 3 quartiles compared with the bottom quartile of the dietary risk score was 30%. </jats:p> <jats:p> <jats:bold> <jats:italic>Conclusions—</jats:italic> </jats:bold> An unhealthy dietary intake, assessed by a simple dietary risk score, increases the risk of AMI globally and accounts for ≈30% of the population-attributable risk. </jats:p>
収録刊行物
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- Circulation
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Circulation 118 (19), 1929-1937, 2008-11-04
Ovid Technologies (Wolters Kluwer Health)