Proteins Required for Centrosome Clustering in Cancer Cells

  • Blanka Leber
    Clinical Cooperation Unit Molecular Hematology/Oncology, German Cancer Research Center and Department of Internal Medicine V, University of Heidelberg, 69120 Heidelberg, Germany.
  • Bettina Maier
    Clinical Cooperation Unit Molecular Hematology/Oncology, German Cancer Research Center and Department of Internal Medicine V, University of Heidelberg, 69120 Heidelberg, Germany.
  • Florian Fuchs
    Division of Signaling and Functional Genomics, German Cancer Research Center and University of Heidelberg, Medical Faculty Mannheim, 69120 Heidelberg, Germany.
  • Jing Chi
    Clinical Cooperation Unit Molecular Hematology/Oncology, German Cancer Research Center and Department of Internal Medicine V, University of Heidelberg, 69120 Heidelberg, Germany.
  • Phillip Riffel
    Clinical Cooperation Unit Molecular Hematology/Oncology, German Cancer Research Center and Department of Internal Medicine V, University of Heidelberg, 69120 Heidelberg, Germany.
  • Simon Anderhub
    Clinical Cooperation Unit Molecular Hematology/Oncology, German Cancer Research Center and Department of Internal Medicine V, University of Heidelberg, 69120 Heidelberg, Germany.
  • Ludmila Wagner
    Clinical Cooperation Unit Molecular Hematology/Oncology, German Cancer Research Center and Department of Internal Medicine V, University of Heidelberg, 69120 Heidelberg, Germany.
  • Anthony D. Ho
    Department of Internal Medicine V, University of Heidelberg, 69120 Heidelberg, Germany.
  • Jeffrey L. Salisbury
    Tumor Biology Program and Department of Biochemistry and Molecular Biology, Mayo Clinic, Rochester, MN 55905, USA.
  • Michael Boutros
    Division of Signaling and Functional Genomics, German Cancer Research Center and University of Heidelberg, Medical Faculty Mannheim, 69120 Heidelberg, Germany.
  • Alwin Krämer
    Clinical Cooperation Unit Molecular Hematology/Oncology, German Cancer Research Center and Department of Internal Medicine V, University of Heidelberg, 69120 Heidelberg, Germany.

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<jats:p>Identified in an RNA interference screen, proteins that prevent spindle multipolarity in human cancer cells may prove to be promising drug targets.</jats:p>

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