Immune perturbations in HIV-1–infected individuals who make broadly neutralizing antibodies

  • M. Anthony Moody
    Duke University Human Vaccine Institute, Duke University School of Medicine, Durham, NC 27710, USA.
  • Isabela Pedroza-Pacheco
    Nuffield Department of Clinical Medicine, University of Oxford, Oxford OX3 7FZ, UK.
  • Nathan A. Vandergrift
    Duke University Human Vaccine Institute, Duke University School of Medicine, Durham, NC 27710, USA.
  • Cecilia Chui
    Nuffield Department of Clinical Medicine, University of Oxford, Oxford OX3 7FZ, UK.
  • Krissey E. Lloyd
    Duke University Human Vaccine Institute, Duke University School of Medicine, Durham, NC 27710, USA.
  • Robert Parks
    Duke University Human Vaccine Institute, Duke University School of Medicine, Durham, NC 27710, USA.
  • Kelly A. Soderberg
    Duke University Human Vaccine Institute, Duke University School of Medicine, Durham, NC 27710, USA.
  • Ane T. Ogbe
    Nuffield Department of Clinical Medicine, University of Oxford, Oxford OX3 7FZ, UK.
  • Myron S. Cohen
    University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.
  • Hua-Xin Liao
    Duke University Human Vaccine Institute, Duke University School of Medicine, Durham, NC 27710, USA.
  • Feng Gao
    Duke University Human Vaccine Institute, Duke University School of Medicine, Durham, NC 27710, USA.
  • Andrew J. McMichael
    Nuffield Department of Clinical Medicine, University of Oxford, Oxford OX3 7FZ, UK.
  • David C. Montefiori
    Department of Surgery, Duke University School of Medicine, Durham, NC 27710, USA.
  • Laurent Verkoczy
    Duke University Human Vaccine Institute, Duke University School of Medicine, Durham, NC 27710, USA.
  • Garnett Kelsoe
    Duke University Human Vaccine Institute, Duke University School of Medicine, Durham, NC 27710, USA.
  • Jinghe Huang
    Laboratory of Immunoregulation, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20814, USA.
  • Patrick R. Shea
    Institute for Genomic Medicine, Columbia University, New York, NY 10032, USA.
  • Mark Connors
    Laboratory of Immunoregulation, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20814, USA.
  • Persephone Borrow
    Nuffield Department of Clinical Medicine, University of Oxford, Oxford OX3 7FZ, UK.
  • Barton F. Haynes
    Duke University Human Vaccine Institute, Duke University School of Medicine, Durham, NC 27710, USA.

Description

<jats:p>Individuals infected with HIV-1 who produce broadly neutralizing antibodies have a distinct immunological landscape.</jats:p>

Journal

  • Science Immunology

    Science Immunology 1 (1), 2016-07-14

    American Association for the Advancement of Science (AAAS)

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