Osteoblast response to the surface topography of hydroxyapatite two‐dimensional films

  • Gai Yang
    Collaborative Innovation Center of Henan Province for Green Manufacturing of Fine Chemicals Key Laboratory of Green Chemical Media and Reactions, Ministry of Education, Henan Normal University Xinxiang Henan 453007 People's Republic of China
  • Zili Liu
    Collaborative Innovation Center of Henan Province for Green Manufacturing of Fine Chemicals Key Laboratory of Green Chemical Media and Reactions, Ministry of Education, Henan Normal University Xinxiang Henan 453007 People's Republic of China
  • Yuming Guo
    Collaborative Innovation Center of Henan Province for Green Manufacturing of Fine Chemicals Key Laboratory of Green Chemical Media and Reactions, Ministry of Education, Henan Normal University Xinxiang Henan 453007 People's Republic of China
  • Jie Zhang
    Collaborative Innovation Center of Henan Province for Green Manufacturing of Fine Chemicals Key Laboratory of Green Chemical Media and Reactions, Ministry of Education, Henan Normal University Xinxiang Henan 453007 People's Republic of China
  • Han Li
    Collaborative Innovation Center of Henan Province for Green Manufacturing of Fine Chemicals Key Laboratory of Green Chemical Media and Reactions, Ministry of Education, Henan Normal University Xinxiang Henan 453007 People's Republic of China
  • Weike Shi
    Collaborative Innovation Center of Henan Province for Green Manufacturing of Fine Chemicals Key Laboratory of Green Chemical Media and Reactions, Ministry of Education, Henan Normal University Xinxiang Henan 453007 People's Republic of China
  • Jing Feng
    Collaborative Innovation Center of Henan Province for Green Manufacturing of Fine Chemicals Key Laboratory of Green Chemical Media and Reactions, Ministry of Education, Henan Normal University Xinxiang Henan 453007 People's Republic of China
  • Kui Wang
    Collaborative Innovation Center of Henan Province for Green Manufacturing of Fine Chemicals Key Laboratory of Green Chemical Media and Reactions, Ministry of Education, Henan Normal University Xinxiang Henan 453007 People's Republic of China
  • Lin Yang
    Collaborative Innovation Center of Henan Province for Green Manufacturing of Fine Chemicals Key Laboratory of Green Chemical Media and Reactions, Ministry of Education, Henan Normal University Xinxiang Henan 453007 People's Republic of China

書誌事項

公開日
2017-01-23
権利情報
  • http://onlinelibrary.wiley.com/termsAndConditions#vor
DOI
  • 10.1002/jbm.a.35967
公開者
Wiley

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説明

<jats:title>Abstract</jats:title><jats:p>In the current study, three hydroxyapatite two‐dimensional films with similar wettability but different topological roughness have been prepared through a facile one‐step method using hydrated polylactic acid discs as substrates. The results indicated that the protein adsorption capabilities of the hydroxyapatite two‐dimensional films and the proliferation of osteoblast cells on the as‐prepared films increased obviously with the increase of the films' roughness. These reveal that the cellular responses to two‐dimensional materials can be efficiently tuned by easily adjusting the topological roughness. This finding affords an efficient strategy to regulate the cellular response to bioinorganic two‐dimensional materials and significantly expanded their application potentials in tissue engineering. © 2017 Wiley Periodicals, Inc. J Biomed Mater Res Part A: 105A: 991–999, 2017.</jats:p>

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