The 5300-year-old <i>Helicobacter pylori</i> genome of the Iceman

  • Frank Maixner
    Institute for Mummies and the Iceman, European Academy of Bozen/Bolzano (EURAC), Viale Druso 1, 39100 Bolzano, Italy.
  • Ben Krause-Kyora
    Institute of Clinical Molecular Biology, Kiel University, Schittenhelmstrasse 12, 24105 Kiel, Germany.
  • Dmitrij Turaev
    CUBE–Division of Computational Systems Biology, Department of Microbiology and Ecosystem Science, University of Vienna, Althanstrasse 14, 1090 Vienna, Austria.
  • Alexander Herbig
    Institute for Archaeological Sciences, University of Tübingen, Rümelinstrasse 23, 72072 Tübingen, Germany.
  • Michael R. Hoopmann
    Institute for Systems Biology, 401 Terry Avenue North, Seattle, WA 98109, USA.
  • Janice L. Hallows
    Institute for Systems Biology, 401 Terry Avenue North, Seattle, WA 98109, USA.
  • Ulrike Kusebauch
    Institute for Systems Biology, 401 Terry Avenue North, Seattle, WA 98109, USA.
  • Eduard Egarter Vigl
    Scuola Superiore Sanitaria Provinciale “Claudiana,” Via Lorenz Böhler 13, 39100 Bolzano, Italy.
  • Peter Malfertheiner
    Department of Gastroenterology, Hepatology, and Infectious Diseases, Otto-von-Guericke University, Leipziger Strasse 44, 39120 Magdeburg, Germany.
  • Francis Megraud
    Université de Bordeaux, Centre National de Référence des Helicobacters et Campylobacters and INSERM U853, 146 rue Léo Saignat, 33076 Bordeaux, France.
  • Niall O’Sullivan
    Institute for Mummies and the Iceman, European Academy of Bozen/Bolzano (EURAC), Viale Druso 1, 39100 Bolzano, Italy.
  • Giovanna Cipollini
    Institute for Mummies and the Iceman, European Academy of Bozen/Bolzano (EURAC), Viale Druso 1, 39100 Bolzano, Italy.
  • Valentina Coia
    Institute for Mummies and the Iceman, European Academy of Bozen/Bolzano (EURAC), Viale Druso 1, 39100 Bolzano, Italy.
  • Marco Samadelli
    Institute for Mummies and the Iceman, European Academy of Bozen/Bolzano (EURAC), Viale Druso 1, 39100 Bolzano, Italy.
  • Lars Engstrand
    Department of Microbiology, Tumor and Cell Biology, Karolinska Institutet, 141 83 Stockholm, Sweden.
  • Bodo Linz
    Department of Veterinary and Biomedical Sciences, Pennsylvania State University, University Park, PA 16802, USA.
  • Robert L. Moritz
    Institute for Systems Biology, 401 Terry Avenue North, Seattle, WA 98109, USA.
  • Rudolf Grimm
    Robert Mondavi Institute for Food Science, University of California, Davis, CA 95616, USA.
  • Johannes Krause
    Institute for Archaeological Sciences, University of Tübingen, Rümelinstrasse 23, 72072 Tübingen, Germany.
  • Almut Nebel
    Institute of Clinical Molecular Biology, Kiel University, Schittenhelmstrasse 12, 24105 Kiel, Germany.
  • Yoshan Moodley
    Department of Zoology, University of Venda, Private Bag X5050, Thohoyandou 0950, Republic of South Africa.
  • Thomas Rattei
    CUBE–Division of Computational Systems Biology, Department of Microbiology and Ecosystem Science, University of Vienna, Althanstrasse 14, 1090 Vienna, Austria.
  • Albert Zink
    Institute for Mummies and the Iceman, European Academy of Bozen/Bolzano (EURAC), Viale Druso 1, 39100 Bolzano, Italy.

説明

<jats:title>Stomach ache for a European mummy</jats:title> <jats:p> Five thousand years ago in the European Alps, a man was shot by an arrow, then clubbed to death. His body was subsequently mummified by ice until glacier retreat exhumed him in 1991. Subsequently, this ancient corpse has provided a trove of intriguing information about copper-age Europeans. Now, Maixner <jats:italic>et al.</jats:italic> have identified the human pathogen <jats:italic>Helicobacter pylori</jats:italic> within the mummy's stomach contents. The strain the “Iceman” hosted appears to most closely resemble pathogenic Asian strains found today in Central and Southern Asia. </jats:p> <jats:p> <jats:italic>Science</jats:italic> , this issue p. <jats:related-article xmlns:xlink="http://www.w3.org/1999/xlink" ext-link-type="doi" issue="6269" page="162" related-article-type="in-this-issue" vol="351" xlink:href="10.1126/science.aad2545">162</jats:related-article> </jats:p>

収録刊行物

  • Science

    Science 351 (6269), 162-165, 2016-01-08

    American Association for the Advancement of Science (AAAS)

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