Antioxidant diterpenoids from the roots of <i>Salvia barrelieri</i>

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<jats:title>Abstract</jats:title><jats:sec><jats:title>Introduction</jats:title><jats:p> The phytochemical and biological studies carried out on <jats:italic>Salvia </jats:italic>species showed that their extracts and constituents have various biological activities.</jats:p></jats:sec><jats:sec><jats:title>Objective</jats:title><jats:p>The aim of this study was the isolation of diterpenoids from the roots of <jats:italic>Salvia barrelieri</jats:italic> Ettling and the determination of the antioxidant activity.</jats:p></jats:sec><jats:sec><jats:title>Methodology</jats:title><jats:p>Chromatographic methods were used for fractionation and isolation, respectively. Structure elucidation was established by spectroscopic methods. Five antioxidant assays were performed.</jats:p></jats:sec><jats:sec><jats:title>Results</jats:title><jats:p>Three new abietane diterpenoids barreliol, royleanone 12‐methyl ether and 7‐epi‐salviviridinol, and six known diterpenoids, with a known dammarane triterpenoid, pyxinol were isolated. The absolute stereochemistry of pyxinol was confirmed by X‐ray analysis.</jats:p></jats:sec><jats:sec><jats:title>Conclusion</jats:title><jats:p>Taxodione exhibited the highest antioxidant activity among the tested compounds. Copyright © 2009 John Wiley & Sons, Ltd.</jats:p></jats:sec>

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