Rhodium(III)‐Catalyzed Amidation of Unactivated C(sp<sup>3</sup>)H Bonds
書誌事項
- 公開日
- 2015-09-07
- 権利情報
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- http://onlinelibrary.wiley.com/termsAndConditions#vor
- DOI
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- 10.1002/anie.201506323
- 公開者
- Wiley
この論文をさがす
説明
<jats:title>Abstract</jats:title><jats:p>Nitrogenation by direct functionalization of CH bonds represents an important strategy for constructing CN bonds. Rhodium(III)‐catalyzed direct amidation of unactivated C(sp<jats:sup>3</jats:sup>)H bonds is rare, especially under mild reaction conditions. Herein, a broad scope of C(sp<jats:sup>3</jats:sup>)H bonds are amidated under rhodium catalysis in high efficiency using 3‐substituted 1,4,2‐dioxazol‐5‐ones as the amide source. The protocol broadens the scope of rhodium(III)‐catalyzed C(sp<jats:sup>3</jats:sup>)H activation chemistry, and is applicable to the late‐stage functionalization of natural products.</jats:p>
収録刊行物
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- Angewandte Chemie International Edition
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Angewandte Chemie International Edition 54 (44), 13049-13052, 2015-09-07
Wiley