Effect of Chronic Immobilization Stress on Tissue Distribution of Vitamin A in Rats Fed a Diet with Adequate Vitamin A

書誌事項

公開日
1982-04
権利情報
  • https://www.elsevier.com/tdm/userlicense/1.0/
DOI
  • 10.1093/jn/112.4.789
公開者
Elsevier BV

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説明

The effect of consecutive daily immobilized stress on the metabolism of vitamin A was studied in rats by following changes in tissue distribution of the vitamin for 14 days. Male rats, fed a diet with adequate vitamin A, were subjected to 4 hours of daily immobilization for 1, 3, 7, 10 or 14 days. Ponderal growth was completely abolished, and serum vitamin A fell markedly. The amount of vitamin A in liver, testes and kidney decreased after the first period of restraint. On the other hand, the amount of vitamin A in adrenal glands increased gradually and reached a maximum (+62.3%) on the 7th day. In conclusion, this experiment showed that daily intermittent immobilization provoked a marked change in distribution of vitamin A in tissues.

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