β-Hematin Interaction with the Hemopexin Domain of Gelatinase B/MMP-9 Provokes Autocatalytic Processing of the Propeptide, Thereby Priming Activation by MMP-3

  • Nathalie Geurts
    Laboratory of Immunobiology and Laboratory of Molecular Immunology, Rega Institute for Medical Research, Catholic University of Leuven, Minderbroedersstraat 10, 3000 Leuven, Belgium
  • Erik Martens
    Laboratory of Immunobiology and Laboratory of Molecular Immunology, Rega Institute for Medical Research, Catholic University of Leuven, Minderbroedersstraat 10, 3000 Leuven, Belgium
  • Ilse Van Aelst
    Laboratory of Immunobiology and Laboratory of Molecular Immunology, Rega Institute for Medical Research, Catholic University of Leuven, Minderbroedersstraat 10, 3000 Leuven, Belgium
  • Paul Proost
    Laboratory of Immunobiology and Laboratory of Molecular Immunology, Rega Institute for Medical Research, Catholic University of Leuven, Minderbroedersstraat 10, 3000 Leuven, Belgium
  • Ghislain Opdenakker
    Laboratory of Immunobiology and Laboratory of Molecular Immunology, Rega Institute for Medical Research, Catholic University of Leuven, Minderbroedersstraat 10, 3000 Leuven, Belgium
  • Philippe E. Van den Steen
    Laboratory of Immunobiology and Laboratory of Molecular Immunology, Rega Institute for Medical Research, Catholic University of Leuven, Minderbroedersstraat 10, 3000 Leuven, Belgium

書誌事項

公開日
2008-02-01
DOI
  • 10.1021/bi702260q
公開者
American Chemical Society (ACS)

この論文をさがす

収録刊行物

  • Biochemistry

    Biochemistry 47 (8), 2689-2699, 2008-02-01

    American Chemical Society (ACS)

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