Electrochemiluminescence Detection in Paper‐Based and Other Inexpensive Microfluidic Devices

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  • Erin M. Gross
    Department of Chemistry Creighton University Omaha NE 68178 USA
  • Hannah E. Durant
    Department of Chemistry Creighton University Omaha NE 68178 USA
  • Kenneth N. Hipp
    Department of Chemistry University of Nebraska-Lincoln Lincoln NE 68588-0304 USA
  • Rebecca Y. Lai
    Department of Chemistry University of Nebraska-Lincoln Lincoln NE 68588-0304 USA

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<jats:title>Abstract</jats:title><jats:p>There is a need in the field of microfluidics for integration of analytical detection methods onto small fluidic chips. Electrogenerated chemiluminescence (ECL) is an effective method for detecting a wide range of analytes, including small molecules, metal ions and bacteria. This Minireview discusses recent applications of ECL‐based detection methods to inexpensive microfluidic devices. We discuss various paper and cloth based devices, including 3D‐origami devices and devices utilizing bipolar electrodes. We also discuss novel devices that have replaced traditional instrumentation with inexpensive and portable equipment, such as mobile phones.</jats:p>

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